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Altindag, Turkey Clinical Trials

A listing of Altindag, Turkey clinical trials actively recruiting patients volunteers.

Found 619 clinical trials

A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLC

THIO is a first-in-class small molecule telomere targeting agent, in development for the treatment of non-small cell lung cancer (NSCLC) in combination with cemiplimab (LIBTAYO®). THIO is preferentially incorporated into telomeres sequence in telomerase-positive cells leading to rapid telomere uncapping, genomic instability, and cell death. Cemiplimab is a programmed cell …

18 years of age All Phase 3

AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL

The purpose of this study is to measure the efficacy and safety of R-mini-CHOP × 2 followed by AZD0486 compared with R-mini-CHOP × 6 in elderly or unfit participants newly diagnosed with LBCL.

65 - 130 years of age All Phase 3
A Alena Turner

TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

The purpose of the study is to evaluate the safety, tolerability, and efficacy of the two different treatment combinations of tulmimetostat in participants with de novo or recurrent Metastatic Hormone-Sensitive Prostate Cancer (mHSPC).

18 years of age Male Phase 1/2

A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

The main purpose of this study is to find out the most suitable dose (recommended phase 2 combination dose \[RP2CD\]) of amivantamab and olomorasib combination therapy and to assess how well the combination slows down or prevents the growth of tumors in participants with KRAS G12C mutant metastatic non-small cell …

18 years of age All Phase 1/2

A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Researchers are looking for a better way to treat people who have advanced non-small cell lung cancer (NSCLC) with specific genetic changes called human epidermal growth factor receptor 2 (HER2) mutations. Advanced NSCLC is a group of lung cancers that have spread to nearby tissues or to other parts of …

18 years of age All Phase 3
Y YILDIZ ERDAT

Effect of "RECAST-H" (REverse CAses STudies Based on Heutagogy Approach) on Professional Readiness

The goal of this study is to examine the effect of reverse case studies based on the heutagogical approach on the level of readiness for the profession among final-year nursing students. The hypotheses are: H0-1: There is no difference in the level of professional readiness between the control group and …

years of age All Phase N/A
A Ayşe Naz Kalem Özgen, Asist. Dr.

Effectiveness of Video-Based or Written Pelvic Floor Education in Postpartum Women

The aim of this study is to evaluate the effect of written or visual information provided outside of routine postpartum follow-up on pelvic floor knowledge and pelvic floor function in women during the postpartum period.

18 - 45 years of age Female Phase N/A
A Ankara Etlik City Hospital Etlik City Hospital

Femoral and Obturator Nerve Articular Branches Prf

In our clinic, patients undergoing pulsed radiofrequency treatment of the femoral and obturator nerve articular branches under ultrasound guidance for pain management due to hip and groin pain associated with hip osteoarthritis will have the efficacy of these methods on pain compared with the Numeric Rating Scale (NRS) and Oxford …

18 - 75 years of age All Phase N/A
S Sila Cagri Isler, Assoc Prof

Reconstructive Treatment of Peri-implantitis With Combined Defects

The aim of this randomized clinical study is to assess the additional clinical benefit of incorporating a resorbable collagen membrane (CM) alongside a xenogeneic bone graft-specifically, deproteinized bovine bone mineral with 10% collagen (DBBM-C)-in the reconstructive surgical treatment of peri-implantitis involving combined (i.e., contained and non-contained) defect configurations. Accordingly, the …

18 - 75 years of age All Phase N/A

Peri-implantitis Treatment With Chitosan Brush

In dentistry, dental implant applications for tooth loss/deficiency are prominent and provide successful long-term results in terms of functionality and aesthetics. However, peri-implant diseases such as peri-implant mucositis and peri-implantitis may develop due to biofilm accumulation around the implant. In peri-implantitis, in addition to the clinical inflammation findings seen in …

18 - 65 years of age All Phase N/A

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