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Esplugues de Llobregat (Barc), Spain Clinical Trials

A listing of Esplugues de Llobregat (Barc), Spain clinical trials actively recruiting patients volunteers.

Found 952 clinical trials

Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid Tumors

The purpose of this trial is to study the antibody GEN1057 when used as a single agent for the treatment of certain types of cancer. Trial details include: The trial duration will be up to approximately 11 months. The treatment duration will be up to approximately 4 months (the duration …

18 years of age All Phase 1
J Julie Etheridge

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 OUS Study)

Characterize the impact of pulmonary artery denervation on the quality of life in Heart Failure Patients with Group 2 Pulmonary Hypertension

22 - 85 years of age All Phase N/A
A Anna Dalmau-Roig, MD

Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain

PAINDOC is a treatment program that includes 4 disciplines that, separately, have demonstrated their effectiveness in the treatment of chronic low back pain: education in pain neuroscience, therapeutic education (Empowered Relief®), psychotherapy based on cognitive-behavioral therapy and therapeutic exercise. The primary objective of the study is to evaluate the effectiveness …

18 years of age All Phase N/A
R Ricard Mellado Artigas, PhD

Physiologic Effects of Continuous Positive Airway Pressure and High Flow Nasal Oxygenation in Patients with Acute Respiratory Distress Syndrome.

The acute respiratory distress syndrome (ARDS) consists on a lack of breath due to fluid overload in the lungs that is not produced by a heart desease. Some people with this condition may need to be intubated and connected to invasive mechanical ventilation, but less severe cases may need supplementary …

18 - 80 years of age All Phase N/A
L Laura Burunat Ruesgas, Chemistry

First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome Carriers

Tha aim of this clinical trial is to evaluate safety and tolerability of autologous peripheral blood differentiated and matured adult dendritic cells. Immunogenicity of the prduct(DC-DELAY) will be evaluated also.

18 years of age All Phase 1
C Catherine Thieblemont, Prof

Integrated Molecular and Clinical Profiling of Transformed Splenic Marginal Zone Lymphoma

Histological transformation in Splenic Marginal Zone Lymphoma (t-SMZL) represents an unmet clinical and biological need, invariably associated with poor prognosis and reduced overall survival. At the present time, there are no recommended treatments intended specifically to t-SMZL and little is known about t-SMZL genetic complexity. The aim of this study …

18 years of age All Phase N/A
E Estela del Mar Sánchez Sotano

Evaluation of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma

This study aims to evaluate the effects of BrudyGlauco, a nutritional supplement containing DHA (docosahexaenoic acid) and citicoline, on visual function in people with glaucoma. Glaucoma is a progressive optic neuropathy that can lead to vision loss. Current treatments focus on lowering eye pressure, but there are other pathogenic factors …

50 - 75 years of age All Phase N/A
J Jose M Guerra, MD, PhD

Evaluation of Two Different Regimens of the Antiarrhythmic Drug Amiodarone to Maintain Normal Sinus Rhythm After Electrical Cardioversion in Patients With Persistent Atrial Fibrillation

\--- The goal of this clinical trial is to learn if reduced doses of amiodarone can treat atrial fibrillation (AF) effectively while minimizing toxic side effects in patients with persistent AF after electrical cardioversion. The main questions it aims to answer are: Can a reduced dose of amiodarone (100 mg/day) …

18 years of age All Phase 4
G Giuseppina Rametti, PhD

Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression

Depression and anxiety are the most prevalent mental disorders among both the general population and young adults, and transdiagnostic treatments for these patients are mostly based on cognitive-behavioral therapy (CBT). Based on common (transdiagnostic) principles of treatment (e.g., emotional exposure), these approaches have proliferated and demonstrated their efficacy in comparison …

16 - 29 years of age All Phase N/A
A Anna Aulinas, MD PhD

Sleep Disorders in Hypothalamic and Pituitary Damage

Hypothalamus has a key role in multiple vital functions, including regulation of sleep-wake cycles. Oxytocin (OT), a neurohormone synthetized in the hypothalamus, has a wide range of physiological functions, including a putative role in improving sleep quality. Hypothalamic and pituitary damage (HPD) is associated with a clinically relevant OT deficient …

18 - 70 years of age All Phase N/A

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