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Groningen, Netherlands Clinical Trials

A listing of Groningen, Netherlands clinical trials actively recruiting patients volunteers.

Found 230 clinical trials
H Hiske van der Weide

Standard Follow-up Program Neuro-oncology Patients (SFP Neuro-Oncology)

Standardised evaluation of baseline data regarding tumor-, patient- and treatment-characteristics as well as follow-up data regarding tumor- and clinical-outcome of neuro-oncology patients treated with radical/curative radiotherapy. Motive Currently there is limited data on dose-effect relationships of tissues and structures in and around the brain. This lack of knowledge hampers patient …

18 years of age All Phase N/A
K K van Kammen, PhD

Rehablines: a Further Use Databank to (re)Use Routine Clinical Data for Scientific Research in Rehabilitation of People With Physical Disabilities and/or Chronic Diseases

Within the Center of Rehabilitation multidisciplinary treatment is provided to people with various physical disabilities and/or chronic diseases. During and in the context of this treatment, a lot of data is routinely collected. Rehablines is initiated to re-use this routine clinical data in a database for future scientific research. Rehablines …

years of age All Phase N/A
F Frank vd Veerdonk, Prof. Dr.

Prospective Observational Trial of IAPA

A prospective multi-center observational study to assess the incidence of influenza-associated pulmonary aspergillosis (IAPA) in ICU patients and to identify host- and pathogen related risk factors for IAPA in EORTC negative ICU patients with severe influenza.

18 years of age All Phase N/A
K Karin Klooster, PhD

Bronchoscopic EmphysemA Treatment in THE NetherLands

Rationale: New bronchoscopic treatments for emphysema have shown promise in clinical trials, improving lung function, exercise capacity and possibly survival and are now being adopted by a number of centres in the Netherlands. It is important to ensure that the benefits seen in clinical trials are in fact reflected in …

years of age All Phase N/A
J J. Nuver, MD, PhD

Early Ageing During Therapy in AYA Cancer Patients

Longitudinal cohort study; measurements before start of systemic therapy and one year later.

18 - 39 years of age All Phase N/A
V Vincent E de Meijer, MD, PhD

Long-term Outcomes After Prolonged Dual Hypothermic Oxygenated Machine Perfusion of Donor Livers (DHOPEPROLONG)

End-ischemic dual hypothermic oxygenated machine perfusion (DHOPE) of human donor livers mitigates ischemia-reperfusion injury, resulting in a reduction of post-reperfusion syndrome, early allograft dysfunction and biliary complications, when compared with static cold storage. End-ischemic DHOPE can be used to prolong donor liver preservation time for up to 24 hours. According …

18 years of age All Phase N/A
L Laurine T van der Wal, MSc

Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study

Rationale: In addition to surgery, effective breast cancer (BC) treatment typically requires chemotherapy, radiotherapy, or both. However, it is still unclear whether patients with BC are at increased risk of long-term cardiac dysfunction due to the adverse effects of these therapies. In a cross-sectional study in primary care, a comparison …

years of age Female Phase N/A

The Role of the Pulmonary Vasculature in the Fontan Circulation

This study aims to explore the structural and functional characteristics of the pulmonary vasculature in adult Fontan patients. Objectives Determine the effect of pulmonary vasodilatation on indexed cardiac output during simulated exercise. Characterization of structural properties of small pulmonary arteries.

18 years of age All Phase N/A
A Anniek Reinhardt, MSc./Drs.

The MS-CEBA Study: Determining Cognitive, Energetic, Behavioural and Affective (CEBA) Profiles in Multiple Sclerosis

Multiple Sclerosis (MS) is an invalidating neurological disease known to cause physical symptoms, which usually are the main focus of treatment. However, non-physical, more neuropsychological, symptoms also frequently occur, concerning the Cognitive, Energetic, Behavioural and Affective (CEBA) domains. Symptoms in the CEBA domains are known to negatively affect societal participation, …

18 - 70 years of age All Phase N/A
M Michiel Rienstra, MD PhD

Value of Intense Phenotyping in Heart Failure With Preserved Ejection Fraction

Heart failure (HF) with a left ventricular ejection fraction (LVEF) >0.40 is a large medical problem, for which no drug or device has a recommendation in current HF guidelines. The prevalence of mortality and HF hospitalizations in HF with LVEF >0.40 is high, but the identification of predictors for increased …

18 years of age All Phase N/A

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