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Tokyo and Other Japanese City, Japan Clinical Trials

A listing of Tokyo and Other Japanese City, Japan clinical trials actively recruiting patients volunteers.

Found 61,726 clinical trials
N Natasha Lemasney

The Effectiveness of Virtual Appointments on Compliance With Twin Block Wear

The investigators aim to determine the effect of virtual appointments on compliance with Twin Block wear. Patients satisfying the inclusion criteria requiring a Twin Block appliance will be requested to participate in the study. Those selected will be allocated to either the intervention or control group. The control group will …

10 - 14 years of age All Phase N/A
D Dejan Micic, MD

Video Training Supplementation for Patients Discharged on Home Parental Nutrition

The goal of this clinical trial is to develop an educational video addressing the aseptic techniques to safely handle central catheters for administrating parenteral nutrition at home.

18 years of age All Phase N/A
P Pierre PAYOUX, MD

MRI and Eye-tracking Predictive Markers of Cognitive Ageing

This research proposes to investigate physiological and cognitive markers of locus coeruleus (LC) neuronal integrity and function in cognitively-healthy participants over 60 years old. The locus coeruleus is a brainstem nucleus, sole source of noradrenaline for the brain. Tau pathology appears in neurons of this nucleus, which may induce initial …

60 - 100 years of age All Phase N/A
S Stuart Mazzone, PhD

Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough

Recently, a new drug called Gefapixant passed phase III clinical trials for cough suppression in patients with chronic cough. The goal of this clinical trial is to investigate the effect of acute and prolonged administration of the drug Gefapixant on cough-related brain activity in patients with chronic cough. The main …

18 - 65 years of age All Phase N/A
M Melissa Malham

The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence

This study will evaluate the compliance with a daily kava regimen among active smokers who have an intention to quit smoking. This study will also investigate whether kava use can facilitate tobacco cessation, reduce stress, and improve sleep.

21 - 99 years of age All Phase 2

Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism

Introduction This study investigates the effects of different intensities of indoor cycling on various health measures. Participants will perform a maximal cycling test to determine their maximal fitness - a strong predictor of overall health - before and after a 6-week training intervention. Blood samples will also be obtained to …

18 - 40 years of age All Phase N/A

Optimizing Treatment of Adhesive Small Bowel Obstruction

Small bowel obstruction (SBO) is one of the most common causes of serious gastrointestinal disease in the US. Adhesion-related SBO (aSBO) is usually treated by the placement of a nasogastric tube (NGT) to decompress the stomach, administration of intravenous (IV) fluids and observation by a surgical team. The purpose of …

18 years of age All Phase 3
L Lindelwa P. Dlamini, MSc

Antenatal Depression Help-seeking Trial in Eswatini

The goal of this trial to test if a web-based psychoeducation will work in improving depression help-seeking intention and behavior among antenatal women with probable depression in Eswatini. The main question it aims to answer is: • Does the web-based psychoeducation improve depression help-seeking intention and help-seeking behavior in antenatal …

18 years of age Female Phase N/A
T Tao Yang, MD

Human Umbilical Cord Mesenchymal Stem Cell Transplantation for The Treatment of Acute-on-Chronic Liver Failure

This study is a randomized double-blind placebo-controlled multicenter clinical trial to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cell (UC-MSC) transplantation for the treatment of acute-on-chronic liver failure (ACLF). UC-MSC therapy may improve the clinical outcomes of patients with ACLF. The trial would provide scientific evidence …

18 - 70 years of age All Phase 1/2
L Lee M Margolis, PhD

Optimized Carbohydrate Fueling to Enhance Physical Performance During Energy Deficit

This randomized crossover study will examine the effects of consuming isocaloric GLU+FRU or GLU alone on rates of exogenous carbohydrate oxidation during aerobic exercise and physical performance (time trial) under energy balance (BAL) and energy deficit (DEF). Baseline data will be collected on volunteer height, weight, body composition, and V̇O2peak. …

18 - 39 years of age All Phase N/A

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