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Tokyo and Other Japanese City, Japan Clinical Trials

A listing of Tokyo and Other Japanese City, Japan clinical trials actively recruiting patients volunteers.

Found 61,726 clinical trials

Dose Escalation and Expansion Study of HM97662 in Advanced or Metastatic Solid Tumors

This is a Phase1 study to assess the safety, PK, PD and efficacy of HM97662, EZH1/2 dual inhibitor, in solid tumors. The study will be conducted in Dose-Escalation and Dose-Expansion parts. Dose-Escalation Part is planned with a 3+3 Dose-Escalation design and is to establish the MTD or RD for Dose-Expansion …

18 years of age All Phase 1
V Veronica Formanek, BS

Nasal Obstruction and Olfactory Losses

About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to …

18 - 70 years of age All Phase N/A
Z Zhenzhen Liu, PhD

Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation

To compare the incidence of glaucoma-related adverse events of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia

18 - 14 years of age All Phase N/A
S Sonjia Kenya, EdD

Integrated Navigation Services for Treatment Adherence, Counseling, and Research

The goal of this research is to determine whether a Community Health Worker (CHW) intervention including a mobile telehealth (M-Health) component can help achieve long term viral suppression among Black people with poorly controlled HIV.

18 years of age All Phase N/A
Y Yunfei Chen, MD

Avatrombopag for Chemotherapy-induced Thrombocytopenia

To evaluate the efficacy and safety of Avatrombopag to treat chemotherapy-induced thrombocytopenia in solid tumors

18 years of age All Phase 2
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array

Background Brain activity produces magnetic fields. These fields can be measured outside the head. Existing technology, called MEG, measures these fields. Researchers are testing a new type of magnetic field sensor called OPM. They hope it can help pinpoint with very high accuracy where brain activity is generated. Objective To …

18 - 65 years of age All Phase N/A
E Elizabeth K Turner

Conservative Management for PAS Pilot

Conservative in situ management is a promising alternative treatment to hysterectomy for patients with placenta accreta spectrum and may be safer and preferable for some patients. This study will assess feasibility of a future randomized clinical trial comparing these treatments and provide novel data to inform shared decision-making and cost-effective …

18 - 99 years of age Female Phase N/A
M Marine JARY, MD

A Clinical-biological Prospective Cohort of Patients With BRAFV600E-mutated Metastatic Colorectal Cancer

The study will be conducted in patients with metastatic colorectal cancer (mCRC) harboring a BRAFV600E mutation, to collect clinical data and biological samples to be used for research but also to gather real-world clinical data concerning the treatments and the survival outcomes in patients with this pathology.

18 years of age All Phase N/A

Advance Care Planning Training for Nurses

The aims of this study are to examine the effectiveness of a multi-media experiential training programme in advance care planning (ACP) for nursing staff in acute care settings. The main questions it aims to answer are: can the programme enhance nurses' decision-support skills can the programme strengthen nurses' knowledge and …

18 years of age All Phase N/A
A Angela Juby, MBChB

Nutritional Management of Post COVID-19 Cognitive Symptoms

The goal of this clinical trial is to learn about in brain "fog" complaints associated with long-COVID in people aged 22-50-years. The main questions it aims to answer are: the natural course of brain "fog" complaints the effect, if any of supplemental dietary oil on brain "fog" complaints Participants will …

22 - 50 years of age All Phase N/A

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