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Tokyo and Other Japanese City, Japan Clinical Trials

A listing of Tokyo and Other Japanese City, Japan clinical trials actively recruiting patients volunteers.

Found 64,712 clinical trials
K Karuna Rajkumar

Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

The purpose of this study is to investigate the intra-abdominal pressure utilizing the Accuryn monitoring system during pulsed field ablation procedures in the electrophysiology lab compared to the type of anesthetic utilized.

18 years of age All Phase N/A
A Ahmad E Mahran, Professor

Noninvasive Technique and High Flow Nasal Oxygen in Respiratory Failure

After obtaining Institutional Ethical Committee approval of Faculty of Medicine, Minia University and written informed consent from patients or first- degree relatives, this prospective randomized non-blind comparative study will be conducted in adult intensive care unit (ICU) of Anesthesia, Intensive Care and Pain management department Minia university hospital over a …

18 years of age All Phase N/A
L Lamprine Whitney

PrP-targeting siRNA Safety & Mechanism Study

The purpose of this trial is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamic impact of PrP-siRNA in symptomatic prion disease patients.

18 years of age All Phase 1
S Stéphanie Cavigioli, dr

Study Evaluating the Effect of Humiome® Post LB on Stress, Anxiety, and Cognition in Aging Adults

To assess the effect of 3 months of daily consumption of a postbiotic (inactivated lactic acid bacteria) Humiome® Post LB on stress measured by the Depression Anxiety Stress Scale-21 (DASS-21) adjusted on baseline in study participants when compared to placebo

50 - 75 years of age All Phase N/A
A Aditya Parikh, MD

Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure

RECOVER HF is a clinical study designed to evaluate the safety and efficacy of Synchronized Diaphragmatic Stimulation delivered using the VisONE System in the treatment of patients with heart failure.

18 years of age All Phase N/A

Multimodal Bio-mechanical Analysis of Adult Spinal Deformity With Sagittal Plane Misalignment

A good understanding of the principles of balance is vital to achieve optimal outcomes when treating spinal disorders. A complex interaction of the neuromotor system and muscular recruitment is necessary for ergonomic balance and deliberate displacement of the human body. Sagittal plane misalignment in spinal deformities challenges balance mechanisms used …

18 - 79 years of age All Phase N/A
J Jani MA Talvilahti, DDS, Head

Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome

This study looks at how jaw surgery called maxillomandibular advancement with counterclockwise rotation affects breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot tolerate standard treatments such as Continous Positive Airway pressure treatment. The participants are followed over time to see whether the surgery improves …

18 - 70 years of age All Phase N/A

Refusal of Sentinel Lymph Node Biopsy in Patients With Luminal A Subtype Early Breast Cancer

Sentinel lymph node biopsy (SLNB) is the standard of axillary lymph node surgical staging in patients with early breast cancer. The main goal of the study is to abandon axillary surgery in patients over 59 years old with early, luminal A, clinical lymph node negative breast cancer.

60 years of age Female Phase N/A
E Eloisa SDO Bonfa, Full Professor

Immunogenicity and Safety of MenB Vaccine in Pediatric Patients With Autoimmune Rheumatic Diseases

The goal of this clinical trial is to evaluate the humoral immunogenicity of the meningococcal B vaccine (MenB-4C) in pediatric patients with autoimmune rheumatic diseases (ARDs), compared to age- and sex-matched non-immunosuppressed controls. The main questions it aims to answer are: To assess the influence of treatment on the response …

2 - 25 years of age All Phase 4
J Jennifer Ramsay

Manganese-enhanced Magnetic Resonance Imaging in Takotsubo Cardiomyopathy

The goal of this research study is to further understand the physiological mechanisms involved in a heart condition called takotsubo cardiomyopathy, also known as broken heart syndrome. Furthermore, the investigators will be assessing the effects different cardiac medications have on these physiological mechanisms. This will be achieved by performing cardiac …

18 years of age All Phase N/A

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