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Torino, Piemonte, Italy Clinical Trials

A listing of Torino, Piemonte, Italy clinical trials actively recruiting patients volunteers.

Found 193 clinical trials
M Mario Aimetti, Prof.

Timing of Re-evaluation After Steps I-II of Periodontal Therapy

Literature on non surgical periodontal therapy (NSPT) shows lack of clarity in reporting information on re-evaluation timing and clinical response. If the re-evaluation was done shortly after NSPT, this is also likely to have an influence on the surgical treatment plan. The aim of this randomized clinical trial is to …

18 years of age All Phase N/A
E Enrico Checcucci

Robotic Hemi-Prostatectomy With Urethral Preservation in Low and Intermediate Risk Monolateral Prostate Cancer

On the basis of the now consolidated literature and clinical experience of focal therapies, the execution of partial prostatectomy/hemiprostatectomy with robot-assisted laparoscopic technique can be proposed in a well-selected cohort of patients. The hypothesis is that with this technique it is possible to achieve excellent levels of disease control, in …

40 years of age Male Phase N/A

Ibrutinib for the Treatment of AIHA in Patients With CLL/SLL or CLL-like MBL

This is a multicenter, single arm, phase II study aimed at evaluating ibrutinib therapy for the treatment of AIHA in patients with CLL/SLL or CLL-like MBL.

18 years of age All Phase 2
A Antonella Brunello, MD

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma

Study is aimed at evaluating the activity of Trabectedin (arm A) in advanced leiomyosarcomas, having Gemcitabine (arm B) as the comparator. In addition to the randomized cohort, the study has also an observational prospective cohort which include patients who will refuse the randomization or for whom the investigator will not …

18 years of age All Phase 2
M Mario Solej, MD

Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer

An Italian randomized controlled trial parallel-group in patients with a malignant tumor of the right or proximal transverse colon requiring right hemicolectomy.

18 - 85 years of age All Phase N/A
A Alessia Pellerino, M.D., Ph.D

SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET)

This study aims to evaluate the efficacy of silibinin in preventing recurrence in the brain after complete resection of a brain metastasis (BM) from non-small-cell lung cancer (NSCLC) or breast cancer (BC).

18 - 70 years of age All Phase N/A
C Carlo Visco

Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients.

This is a prospective, phase 2, multicenter, open-label, single-arm study. Primary objective is to assess the efficacy of loncastuximab tesirine given as consolidation therapy after salvage immunochemotherapy in BTKi (Bruton Tyrosine Kinase inhibitors) -treated (or BTKi intolerant) R/R (Relapse or Refractory) MCL (Mantle Cell Lymphoma) patients. The sponsor of this …

18 - 79 years of age All Phase 2
L Lorenzo Pia, PhD

IVR in Motor Rehabilitation

The present project on sport rehabilitation aims at validating a rehabilitation protocol in immersive virtual reality (IVR) for restoring motor functions following peripheral injuries of the lower limbs. Sport injuries are related to direct and indirect costs and, in many cases, cause an interruption of motor activity for prolonged periods. …

18 - 65 years of age All Phase N/A
F Falcone Mr Marco, Physician

Risks and Benefits of Scrotal Drainage in Penile Prosthesis Implant

The goal of this prospective randomized study is to demonstrate if the use of an external scrotal drainage in penile prosthetic surgery can reduce the risk of post-operative complications without increase the risk of infections.

18 - 90 years of age Male Phase N/A

Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients

The aims of this study are to evaluate if an intensified adjuvant treatment with FOLFOXIRI could increase the rate of cases with undetectable ct-DNA after chemotherapy and to evaluate if a further adjuvant treatment with Trifluridine/Tipiracil could increase the rate of cases with undetectable ct-DNA and therefore improve DFS in …

18 - 75 years of age All Phase 2

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