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HK, Hong Kong Clinical Trials

A listing of HK, Hong Kong clinical trials actively recruiting patients volunteers.

Found 655 clinical trials
M Michael Tim-Yun Ong

Vitamin D to Improve Quadricep Muscle Strength

Quadriceps muscle strength is one of the key determinants for patients to fulfill the Return-to-Play (RTP) criteria after an anterior cruciate ligament reconstruction (ACLR), in which the muscle size is directly linked to muscle strength. Quadriceps muscle atrophy is unavoidable after ACLR, but the rehabilitation program should increase quadriceps muscle …

18 - 40 years of age All Phase 2
S Stephen Lam Cham

CXD101 in Immunotherapy-related Liver Cancer

For hepatocellular carcinoma (HCC), durable responses and improved survivals have been reported in clinical trials on immune checkpoint inhibitor (ICI)-based treatment. However, resistance to ICI is increasingly encountered in clinical practice in HCC patients. Various approaches are currently evaluated in clinical setting to tackle acquired resistance during treatment of ICIs …

18 years of age All Phase 2
M Mike Law, BSc

Immunotherapy and Radioembolisation for Metastatic Hepatocellular Carcinoma

Hepatocellular carcinoma is one of the most intractable primary malignancies in the hepatobiliary and pancreatic tract with a poor overall survival worldwide. Unfortunately, the vast majority of hepatocellular carcinoma patients suffer from advanced unresectable or metastatic disease at diagnosis. Currently targeted therapy alone, or in combination with anti-vascular endothelial growth …

18 years of age All Phase 2
A Allen MY Cheong, PhD

Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) - Randomized Controlled Trial Using Combined Perceptual Learning and Transcranial Electrical Stimulation for Vision Enhancement

Glaucoma is a complex disease that can result in progressive vision loss. It is the second leading cause of blindness, accounting for 23% of permanent blindness in Hong Kong. There are no treatments that restore vision lost to glaucoma. However, recent studies have shown that vision can be improved by …

18 - 80 years of age All Phase N/A
H Harinder Gill, MD

Frontline Oral Arsenic Trioxide for APL

The investigators have formulated an oral preparation of arsenic trioxide (oral-ATO), and shown that it is efficacious for APL in R1, inducing CR2 in more than 90% of patients [8,9]. Furthermore, in an effort to prevent relapse, the investigators have moved oral-ATO forward to the maintenance of CR1. This strategy …

years of age All Phase 2

Olfactory Training on Smell Dysfunction Patients in HK

Causes of olfactory dysfunction can be classified into conductive and sensorineural causes. Conductive causes are mainly due to structural nasal problem, which can be treated by nasal surgery Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. Olfactory Training is well established …

18 - 70 years of age All Phase N/A
A Allen MY Cheong, PhD

Learning Study: Improving Vision in Adults With Macular Degeneration

The purpose of this study is to test whether a kind of brain stimulation called anodal transcranial direct current stimulation (a-tDCS) can be combined with perceptual learning to improve the ability of people with age-related macular degeneration (AMD) or juvenile macular degeneration (JMD) to read words presented to them on …

18 years of age All Phase N/A
J Jennifer Ka Yee Ko, MBBS

Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy

Endometriosis is a chronic inflammatory disease that affects approximately 10-15% of women of reproductive age. Symptoms include dysmenorrhoea, chronic pelvic pain, dyspareunia and infertility. Removal of the endometriotic cyst (chocolate cyst) by surgery is a well-established treatment for symptomatic relief. However, recurrence of endometriotic cyst after surgical removal of the …

18 - 45 years of age Female Phase N/A
M Michael Tim-Yun Ong

Routine Use of Negative Pressure Wound Therapy THR TKR RCT

Negative pressure wound therapy (NPWT) for post total joint arthroplasty incisions has demonstrated benefits in reducing wound complications. A prospective randomized trial will be conducted including 40 patients who will undergo total knee and total hip arthroplasty. The number of wound complications within 21 days will be recorded. As well, …

50 years of age All Phase N/A
J Jessie Tsang

Adjunctive Bright Light Therapy in Patients With Bipolar Depression and Eveningness

This is a randomized placebo-controlled trial to examine the efficacy of six-week bright light therapy as adjunctive treatment for patient with bipolar depression and eveningness.

18 - 65 years of age All Phase N/A

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