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Berlin, Germany Clinical Trials

A listing of Berlin, Germany clinical trials actively recruiting patients volunteers.

Found 551 clinical trials

A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or Obesity

This clinical study is testing two versions of the study medicine cagrilintide. The purpose of the study is to compare these two versions to understand their effects in participants with overweight or obesity. Participants will receive either cagrilintide version D or cagrilintide version B, and which treatment participants receive is …

18 - 64 years of age All Phase 1

Clinical Study on High-fiber Diet and Short-term Fasting in Melanoma Under Immunotherapy With Checkpoint Inhibition

The treatment of melanoma has improved significantly in recent years. A modern form of cancer treatment known as immunotherapy with checkpoint inhibitors plays a key role in this. These drugs help the immune system better recognize and fight cancer cells. Nevertheless, it remains a challenge to maximize treatment effectiveness while …

18 years of age All Phase N/A

A Trial to Compare Treatment With Surlorian (ARM210, S48168) to Placebo in Effects on Muscle Strength and Safety in Adults With Autosomal Dominant RYR1-related Myopathy

This study is testing a medicine called surlorian in adults who have a genetic muscle condition known as autosomal dominant RYR1-related myopathy (RYR1-RM). The goal is to find out whether surlorian improves muscle weakness, and whether it is safe and well tolerated.

18 - 65 years of age All Phase 2
E Evgenii Shumilov, PD, MD

Combining Loncastuximab Tesirine and Epcoritamab in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)

This is a phase II study designed to evaluate the toxicity and efficacy of the combination of loncastuximab tesirine and epcoritamab in patients with relapsed/refractory aggressive B-cell lymphoma. Chimeric antigen receptor (CAR)-T cell naive patients who have failed first-line therapy and patients who have received CAR-T cells as second-line therapy …

18 years of age All Phase 2
C Claudia Spies, MD, Prof.

Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers

The aim of the study is to evaluate circadian glucose, activity and dietary rhythms, as well as metabolic and cardiovascular risk associated with night shift work, sleep quality and well-being in a cohort of hospital staff, comparing employees with night shifts to employees without night shifts.

18 - 67 years of age All Phase N/A
N Nele Wagener, Dr. med.

Preoperative Fasting and the Gut Microbiome Before Hip Replacement

Postoperative complications occur in 5-15% of patients undergoing elective primary total hip arthroplasty (THA), including periprosthetic joint infection (PJI), thrombosis, wound healing disorders, and metabolic dysregulation. The gut microbiome and the systemic immune profile have both been implicated as modifiable contributors to perioperative complication risk. Preoperative therapeutic fasting has been …

18 - 75 years of age All Phase N/A
L Lena-Luise Becker, Dr. med.

International Registry for TRPM3-associated Disorders

The goal of the TRPM3Care-registry is to record the disease progression of patients with TRPM3-associated disorders. This allows us to compare the disease progression and the success of different therapies, as well as to examine their impact on quality of life.

years of age All Phase N/A
M Markus Bock, Dr. med.

Scapholunate Ligament Reconstruction Using Modified Flexor Carpi Radialis Tenodesis

Retrospective study of patients who underwent a modified flexor carpi radialis (FCR) tenodesis for scapholunate ligament injury at Waldfriede Hospital during the period 2016-2026. Primary outcome: Functionality of the operated wrist measured using the validated DASH questionnaire.

18 years of age All Phase N/A

A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants

This study is being done to understand how much of the medicine (CDR132L) enters the bloodstream after injection under the skin compared to injection into a vein in healthy people. This will help us find the best way to give the medicine to people living with heart failure. The study …

18 - 55 years of age All Phase 1
L Lena-Luise Becker, Dr. med.

Exspanding the Knowledge About TNPO2-Associated Disorders

The Target-TNPO2 is an international, multicenter observational registry designed to collect comprehensive clinical, genetic, neurodevelopmental, and longitudinal data from individuals with pathogenic or likely pathogenic variants in the TNPO2 gene. This aids to improve the knowledge and clinical progression on TNPO2-associated disorders. The investigators further aim to provide new insides …

years of age All Phase N/A

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