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Berlin, Germany Clinical Trials

A listing of Berlin, Germany clinical trials actively recruiting patients volunteers.

Found 423 clinical trials

Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD

Pro-Kids is a multi-center, double-blind, randomized and placebo-controlled intervention study in children with chronic kidney disease. The investigators address the effect of a dietary food supplementation of propionic acid on the immune system and the function of the intestinal barrier in CKD patients treated with hemodialysis.

12 - 20 years of age All Phase N/A
P Piet E. Adler, M.Sc.

Family-based Telemedicine vs. Inpatient Anorexia Nervosa Treatment (FIAT)

The FIAT study is funded by the Innovationsfonds of the German Ministry of Health via the DLR Project Management Agency. The study will be conducted in up to 21 hospitals across Germany and in collaboration with 10 German public health insurance companies. The primary aim of this study is to …

8 - 17 years of age All Phase N/A
G Gabriele Eden, Dr. med.

Clinical Performance of the New Plasma Filter PX2 in TPE Treatments

The plasma filter is applied for a single use in extracorporeal blood purification therapy. The intended purpose is the separation of plasma from blood by filtration, in conditions, which are associated with increased concentration of plasma components where a rapid depletion slows down or stops a pathogenic process. The investigation …

18 years of age All Phase N/A

Ultra-high-caloric, Fatty Diet in ALS

This study aims at evaluating efficacy and tolerability of an ultra-high-caloric, fatty diet (UFD) compared to placebo in patients with amyotrophic lateral sclerosis (ALS).

18 years of age All Phase N/A
P Principal Investigator

A Phase 1 Study of GTX-B001 in Healthy Subjects and Patients With Chronic Inducible Urticaria

This is a first-in-human study aimed at determining the safety of a single dose of GTX-B001 in healthy participants and in people with chronic inducible urticaria.

18 - 75 years of age All Phase 1
T Till F Althoff, M.D.

Personalized Atrial Fibrillation Ablation Guided by Non-Invasive Global Mapping

This pilot study investigates if non-invasive global mapping can guide catheter ablation of atrial fibrillation (AF) by defining personalized targets based on the temporal Stability of local Atrial High-Rate Activity (SAHRA). The study also assesses efficacy and safety of this approach and evaluates potential signals of harm. The main questions …

18 years of age All Phase N/A

A Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab

This is an open-label, phase 1/2, multiple-indication platform study to explore safety, potential predictive immune-related biomarkers, and early efficacy (as measured by objective response rate \[ORR; Cohorts 1,2, 4,and 5\] and disease control rate \[DCR; Cohort 3\]) in patients with advanced or metastatic gastrointestinal (GI) tumors. Cohorts 1-4 are not …

18 years of age All Phase 1/2
R Roberto Berni Canani, MD

Effect of a Hydrolyzed Rice Protein-based Formula on Growth, Tolerance, and Health-related Quality of Life in Infants With Cow's Milk Protein Allergy.

The main purpose of this study is to demonstrate that the growth of infants fed with the Test Formula is non-inferior those fed with the Control Formula. The study will also evaluate the gastrointestinal tolerance, quatliy of life and acceptability of the new rice protein-based formula in infants with cow's …

- 8 years of age All Phase N/A
J Jan C Clausen, MD

Influence of Lung Volume Optimization Maneuver in Ventilated Children on Cardiac Output and Lung Compliance in Children With Congenital Heart Disease Undergoing Surgical Repair and in Children Requiring ECMO for Respiratory Failure

The goal of this randomized interventional clinical trial is to learn if a standardized lung volume optimization maneuver is beneficial in children undergoing biventricular repair of their congenital heart disease and in children on ECMO. The main questions it aims to answer are: Does a standardized PEEP-Titration maneuver, to optimize …

- 18 years of age All Phase 1/2

Study to Evaluate Long-term Effectiveness and Safety, Patient Characteristics and Subjective Patient-reported Outcomes of Dupilumab in Patients With Chronic Obstructive Pulmonary Disease (COPD) Under Real-world Conditions

Study to evaluate the change of health-related quality of life, patient characteristics, efficacy and safety in Chronic Obstructive Pulmonary Disease (COPD) patients with Dupilumab therapy in a real-world setting over 24 months.

18 years of age All Phase N/A

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