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All Participating Sites, Germany Clinical Trials

A listing of All Participating Sites, Germany clinical trials actively recruiting patients volunteers.

Found 65,259 clinical trials

Biological Reaction of Direct 3d Printed Retainers

The aim of this study will be to evaluate the biological reaction of direct three dimensional printed retainers. Primary objective is to evaluate bacterial growth and color stability between different thicknesses of 3d printed material used as a retainer . Secondary objective is to determine the optimal thickness for use …

years of age All Phase N/A
P Paolo Carosi, PhD

New Stereophotogrammetry System to Capture Complete-arch Impression

Patients in need of complete arch restorations will be treated with dynamic navigation system. Once the implants are positioned, a new system of stereophotogrammetry will record the implant positions to capture a precise impression to deliver a fixed screw retained interim prosthesis

years of age All Phase N/A
S Solenne Kermarrec, MD PhD

To Disclose a Child Sexual Abuse Within Child & Adolescent Psychiatry Services

Mental health professionals investigating child sexual abuse (CSA) among children and adolescents is a major public health challenge. Many studies have shown the obstacles to disclose, with professionals having difficulties to address this issue and survivors having difficulties to disclose. Many children, old enough to tell what happened to them, …

12 - 25 years of age All Phase N/A
H Haonan Yu, MD

Hydroxyephedrine PET/CT in Sympathetic Nervous System Disease

To evaluate the potential usefulness of 11C/18F-HED positron emission tomography/ computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various Tau-related disease patients.

18 - 80 years of age All Phase N/A
K Konstantinos Tyriakidis, MD

Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Despite improvements in treatment, metastatic prostate cancer remains incurable, especially in the case of pretreated metastatic castration-resistant disease (mCRPC), where treatment options are limited, leading to an unmet need. The paradigm shift in the treatment of metastatic hormone-sensitive prostate cancer (mHSPC) has affected the treatment landscape for mCRPC patients. Many …

18 years of age Male Phase 2
F Frederik Lars Giesel, Univ.-Prof. Dr. med.

Diagnostic Performance of [18F]PSMA-1007 in the Context of Biochemical Recurrence of Prostate Cancer

Following numerous retrospective studies and Phase-3-Studies with promising results, \[18F\]PSMA-1007 has been approved by european authorities. Therefore, it is a growing deployment of this diagnostic method anticipated. This study aims to investigate the diagnostic performance and clinical impact in a real-world-evidence in the context of regular clinical care. The evidence …

18 years of age Male Phase N/A
L Lan NL Tu, PhD

Assessing Systemic Treatment and ctDNA Monitoring Efficacy in Metastatic Cancer Patients Using K4Care Testing.

The goal of this observational study is to investigate the real-world treatment landscape of patients with metastatic cancer and determine the role of ctDNA in monitoring treatment response in patients with metastatic cancer who have undergone K4Care testing

years of age All Phase N/A
A Annalisa Fontana

Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma

RR001, a cell-based gene therapy administered following chemotherapy cycles for the treatment of patients with locally advanced pancreatic cancer. Phase I /IIa clinical trial (open label and non-randomized) to test the effects (safety \& efficacy) of increasing doses of RR001

18 years of age All Phase 1/2
J Joanne Serra

Juveena Hydrogel System Feasibility Study for Heavy Menstrual Bleeding (HMB)

This is a prospective, multicenter, single-arm interventional feasibility study to evaluate the safety and feasibility of the Juveena Hydrogel System for temporary control of heavy menstrual bleeding (HMB) in women with a history of chronic ovulatory HMB.

18 - 45 years of age Female Phase N/A

A Study to Document and to Further Describe Long-term Safety and Effectiveness of Palovarotene in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

The participants in this registry study will have fibrodysplasia ossificans progressiva (FOP). FOP is an ultra-rare, severely disabling disease characterized by new bone formation in areas of the body where bone is not normally present (heterotopic ossification (HO)). HO is often preceded by painful, recurrent episodes of soft tissue swelling …

8 years of age All Phase N/A

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