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Clichy cedex, France Clinical Trials

A listing of Clichy cedex, France clinical trials actively recruiting patients volunteers.

Found 1,936 clinical trials
M Mathilde Doyard

A Natural History Study in Children With a Type II Collagen Disorder With Short Stature

There are relatively few data available on type II collagen disorders, and evidence is lacking on the disease course in relation to symptoms and development of complications, the level of actual disease burden over time as well as data to support identification of possible risk factors. This study aims to …

- 12 years of age All Phase N/A
M Martin Dres, MD phD

Incidence and Impact of ICU-acquired Diaphragm Weakness

ICU survivors are at an increased risk of hospital and ICU readmission. Among the complications of ICU stay, diaphragmatic dysfunction is common, with a prevalence of 60 to 80%, and is associated with increased mortality and prolonged hospital stays. Furthermore, several studies have reported that the observation of impaired respiratory …

18 years of age All Phase N/A
O Odile LAUNAY, MD

Evaluation of Long-term Immunogenicity of a Boost Dose of MVA-BN Vaccine

This study is to evaluate the long-term immunogenicity of a boost dose of MVA-BN vaccine

18 years of age All Phase N/A

Impact of Bacterial Expression and Immune Response in the Severity of Pertussis

The resurgence of pertussis is associated with an evolutionary mechanism under the pressure of current acellular vaccines, with a possible impact on vaccine effectiveness and disease expression. Little is known about the mechanisms involved in the clinical variability of pertussis, including its most severe malignant form observed in infants (mortality …

- 15 years of age All Phase N/A
M Martin Dres, MD phD

Effects of Nasal Ventilation on Cerebral and Pulmonary Function in Orally Intubated Patients

The passage of air through the nasal cavity generates rhythmic oscillations transmitted by the olfactory bulb to the brain, which induces cerebral activation in functional areas and is associated with better cognitive performance compared to oral breathing. Consequently, the abolition of nasal ventilation in patients intubated via the orotracheal route …

18 years of age All Phase N/A
F Frédéric CLARENCON, Pr

Liquid Biopsies for the Detection of Somatic Mutations in bAVMs

"Personalized medicine has revolutionized patient care, particularly in oncology. Brain arteriovenous malformations (bAVMs) are abnormal vessels located on the surface of the brain or within the brain parenchyma, causing abnormal communication between arterial and venous networks, without the interposition of the capillary bed. The main risk of these malformations is …

18 years of age All Phase N/A

Hematological Anomalies in Children With Rasopathy

During childhood, patients with RASopathies (Noonan syndrome and related diseases) can harbor various hematological anomalies ranging from isolated monocytosis, myelemia, thrombocytopenia or splenomegaly to myeloproliferative disorders. These anomalies may spontaneously disappear or persist, sometimes leading to juvenile myelomonocytic leukemia. Guidelines for initial screening and subsequent hematological follow-up have recently been …

- 15 years of age All Phase N/A
b bouchra benkessou, chef de projet

Study of Transaxillary Robotic Thyroidectomy Versus Standard Open Thyroidectomy: Prospective, Comparative Single-Center Study

The aim of our study is to evaluate the two surgical approaches, standard thyroidectomy and robotic thyroidectomy, in terms of postoperative pain management, scar quality, quality of life, as well as the occurrence of postoperative complications (hypocalcemia, compressive cervical hematoma and nerve stimulation)

18 years of age All Phase N/A

Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness

The purpose of this study is to determine if the use of emotional sound as subject own name (SON) pronounced by a familiar voice (FV) compared to SON pronounced by a non-familiar voice (NFV) during event related potential (ERP) produced a more reliable neurophysiological P300 responses, and to assess the …

18 years of age All Phase N/A

Users of Remote Conferencing and Compression of Sound Dynamics : Auditory Effects

The COMPRESSED project is a descriptive, bi-centric and non-invasive study carried out by the CERIAH - IDA - Institut Pasteur and the Haute École Léonard de Vinci in Brussels on volunteer participants identified in two groups : be subject to high exposure to compressed sound, as defined by professional participation …

18 years of age All Phase N/A

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