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A, Kuopio N Clinical Trials

A listing of A, Kuopio N clinical trials actively recruiting patients volunteers.

Found 11,558 clinical trials

A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years

Characterize the safety, tolerability and pharmacokinetics of ORX489 following single and multiple doses.

18 - 60 years of age All Phase 1
M Molly K Courish, MSc, PhD(s)

The Role of EDHFs on Blood Pressure Following a Bout of Prolonged Sitting

Canadians spend most of their day in sedentary postures (i.e., sitting, lying, reclining). While the beneficial impacts of physical activity on the heart are well-established, less is known about the consequences during time spent in sedentary postures. Currently, we know that spending time in a bout of uninterrupted sitting disrupts …

18 - 65 years of age All Phase N/A

A Phase 1/2 Study of GW5282 in Participants With Advanced Solid Tumors

This is a phase 1/2, open-label, multicenter study assessing the safety, tolerability, pharmacokinetics and efficacy of GW5282 in participants with locally advanced or metastatic solid tumors. This study comprised of a dose escalation phase to determine the MTD and the RP2D and a dose expansion phase to further explore the …

18 years of age All Phase 1/2
A ASCEND-IBD Trial Center

A First-in-Human Single and Multiple Ascending Dose Study of MT-251

A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Doses of MT-251 in Healthy Participants

19 - 55 years of age All Phase 1
E Emma V Sanchez-Vaznaugh, ScD

Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men. The main questions the study aims to answer are: Does the intervention improve sexual risk behaviors? Does the intervention increase self-esteem and social support? Are …

18 years of age All Phase N/A
S SHEN LIN

A Study of JMKX005425 in Patients With MSI-H/dMMR Advanced Solid Tumors

This is a first-in-human, Phase I, open-label, multi-center, dose-escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of JMKX005425 in subjects with microsatellite instability-high (MSI) and/or mismatch repair deficiency (dMMR) advanced solid tumors.

18 - 80 years of age All Phase 1

Deucravacitinib for Patients With Moderate/Severe Psoriasis: A Real-Life Experience in Italy

The purpose of this study is to characterize the real-life experience of patients with moderate/severe psoriasis receiving deucravacitinib treatment, in terms of efficacy, safety, and health-related quality of life (HRQoL) in Italy

18 years of age All Phase N/A
D Dr. Cynthia Mohr, PhD

Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking

Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a motivator and supportive factor in changing their partner's alcohol use, but little evidence exists on the specific ways …

18 years of age All Phase N/A
F Francis B Stephens, PhD

Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment

This study aims to investigate the effect that a structured, progressive resistance exercise program may have on maintaining the muscle mass and physical function of overweight/ obese females whilst they experience a tirzepatide (GLP-1/GIP receptor agonist) induced weight loss. Overweight and obese females aged 25-50 will be recruited for the …

25 - 50 years of age Female Phase N/A
R Roya Dastjerdi, MPH

A Study for the PanCystPro Assay in the Management of Pancreatic Cystic Lesions

The purpose of this research is to learn if the PanCystPro assay can help doctors in making decisions about treatment and monitoring of pancreatic cysts. The PanCystPro test measures glucose, carcinoembryonic antigen (CEA), and gastricsin biomarkers on fluid obtained from a pancreatic cyst. The test reports if the cyst fluid …

18 years of age All Phase N/A

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