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A, Kuopio N Clinical Trials

A listing of A, Kuopio N clinical trials actively recruiting patients volunteers.

Found 11,558 clinical trials

Thalamus Seizure Detection With a Deep Brain Stimulator System

The purpose of this study is to determine the feasibility of chronic ambulatory thalamus seizure detection. The sensitivity, specificity, and false alarm rate of thalamus seizure detection will be calculated using recordings from a deep brain stimulation system, assessed relative to concurrent gold-standard video-EEG monitoring collected in the in-patient setting …

18 years of age All Phase N/A

A Novel Intervention for Weight Loss in Young Adults

Obesity and cardiometabolic risks are significant public health issues, with about two-thirds of U.S. adults overweight or obese. Weight loss can prevent these health problems, but current lifestyle interventions have limited success. New, effective strategies are needed to address this rising issue at the population level. The goal of this …

18 - 40 years of age All Phase N/A

Stability of Hemiparetic Patients During a Daily Complex Task

Among the repercussions of hemiparesis following stroke, disturbed stability is responsible for a high risk of falls. Picking up objects from the ground, frequently trained in rehabilitation due to its risk of falling and its frequency in daily life, is a task requiring balance. To date, however, it has been …

18 years of age All Phase N/A
Z Zvinka Z Zlatar, PhD

Promoting Physical Activity in Older Hispanic/Latino(a) Adults

In this randomized controlled trial, study staff will randomize 130 Hispanic/Latino adults without dementia and over age 55 from Southern California and from Kaiser Permanente Washington (State) to either the culturally adapted De Pie physical activity intervention or an active comparison program focusing on general brain health topics. The purpose …

55 - 89 years of age All Phase N/A
J James B Brock, MD

A Mobile Gaming App to Improve Adherence to PrEP

In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi. Formative evaluation interviews will be conducted with stakeholders (healthcare workers, clinic administrators, and patients taking PrEP) to …

15 - 34 years of age All Phase N/A

A Study of EBC-129 in Advanced Solid Tumours

This study will assess the safety and tolerability of EBC-129 as a single agent and in combination with pembrolizumab in patients with advanced solid tumours

18 years of age All Phase 1
W Wei Zhao, Phd

A Phase I Study of KLA318-2 Nanocrystal Injection

The purpose of this study is to evaluate the safety,tolerability and pharmacokinetics properties of KLA318-2 Nanocrystal Injection after a single intravenous injection in healthy participants.

18 - 45 years of age All Phase 1
N Nancy Kuntz, MD

Real-World Efgartigimod Effectiveness in CIDP: A Prospective Study

The aims of this study are to assess the real-world effectiveness of efgartigimod in treating chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), describe the "treatment journey" of participants with CIDP, and assess the utilization of health care services among adult participants with CIDP who initiate treatment with efgartigimod. As this is a …

18 years of age All Phase N/A
C Caroline Cummings, PhD

Pilot Testing a Novel Approach to Pediatric Obesity Treatment

The goal of this clinical trial is to learn if an emotion regulation and self-monitoring intervention can help treat overweight and obesity in teens. The main question it aims to answer is: Does emotion regulation and self-monitoring help reduce biases in teens with overweight and obesity? Do changes in biases …

11 - 14 years of age All Phase 1/2
S Sergej M Ostojic, MD, PhD

Creatine HCl Supplementation in Sarcopenia: A Randomized Controlled Study

The CONCRET-SARCOPA trial is a 12-week, double-blind, randomized controlled study designed to evaluate the efficacy of creatine HCl supplementation in older adults with sarcopenia. The trial investigates whether daily creatine HCl improves body composition, enhances functional muscle and cognitive performance, and favorably alters key blood biomarkers associated with muscle health …

60 years of age All Phase N/A

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