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Weston, Canada Clinical Trials

A listing of Weston, Canada clinical trials actively recruiting patients volunteers.

Found 1,354 clinical trials
M Mrinalini Balki, MD

Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean Delivery

Postpartum hemorrhage (PPH) is a leading cause of maternal mortality, and its severity has been increasing globally, including in high-income countries. The most common cause of PPH is uterine atony occurring in about 70% of cases. Uterotonic agents, like oxytocin, are key in managing the third stage of labour to …

18 - 45 years of age Female Phase N/A
S Shekoufeh SS Salamat, Ph.D.

The Effect of Dairy Intake on Body Weight and Composition and Metabolic Health in Adolescents and Seniors

The goal of this study is to examine how regular dairy intake affects body weight, body composition, and metabolic health in overweight and obese adolescents (ages 15-18) and older adults (ages 60-80) over six months. We are inviting eligible individuals to participate in this study at the Nutrition Intervention Center, …

14 - 80 years of age All Phase N/A
C Clinical Research Group

Study of COYA 302 for the Treatment of ALS

The ALSTARS trial will be conducted across 20-25 sites in the US and Canada, and will evaluate the safety and efficacy of an investigational treatment called COYA 302 for adults with Amyotrophic Lateral Sclerosis (ALS). COYA 302 is an investigational and proprietary biologic combination therapy with a dual immunomodulatory mechanism …

18 - 80 years of age All Phase 2
A Ariana Walji, BSc, MSc Candidate

AI and Safety in Laparoscopic Cholecystectomy: A Randomized Controlled Trial

Today, the majority of gallbladder removals surgeries are done using minimally invasive techniques through small cuts to help patients recover faster. However, these procedures are technically more challenging because surgeons have a restricted view of the patient's anatomy, which can increase the risk of serious complications. Artificial intelligence (AI) tools …

18 years of age All Phase 3
M Madlene Research coordinator

rTMS for Youth Inpatients With Depression

Youth aged 15-24 are likelier to have depression than all age groups in Canada. One-third of depressed youth do not respond to psychotherapy and/or antidepressant medications. A treatment called repetitive transcranial magnetic stimulation or rTMS has proven helpful in adolescents and young adults whose depressive symptoms have been difficult to …

14 - 19 years of age All Phase N/A
S Samira Taeb, MSc

Positron Emission Mammography and Liquid Biopsy in Women With High-risk Breast Screenings

The goal of this research study is to evaluate the performance of two experimental tests, namely Liquid Biopsy and Positron Emission Mammography (PEM) in women at high risk of breast cancer. The plan for this study is to assess whether findings from the combination or each individual test can assist …

18 years of age Female Phase N/A
Z Zujaja-Tul-Noor Zujaja-Tul-Noor, MSc

Weaning is Winning? (WeWin Study)

We propose a multicenter prospective study on pediatric patients with intestinal failure (IF) who weaned off parenteral nutrition (PN).

- 18 years of age All Phase N/A
P Philip Gerretsen, MD, PhD

Neuromodulation for Schizophrenia

Our proposed study employs a novel approach to determine the clinical and functional imaging effects of brainstem neuromodulation, with an investigational study device, on illness awareness in schizophrenia - a significant contributor to medication non-adherence and poor treatment outcomes, and arguably the most treatment resistant manifestation of the disorder. The …

18 years of age All Phase N/A
C Carlos Roncero, PhD

Investigating if a Stronger tDCS Intensity is More Effective for Improving Naming Ability in People Living With Alzheimer's Disease

There is currently little symptomatic therapy for Alzheimer's Disease (AD) and nothing effective for individuals with Frontotemporal dementia (FTD). However, neuromodulation with transcranial direct current stimulation (tDCS) has the potential to be a clinically effective therapy for both AD and FTD. The challenge now is to specify the parameters and …

50 - 90 years of age All Phase N/A
A Andrew Legatto

Digital Technology for Sleep and Homelessness

In Canada, 35,000 people are experiencing homelessness on any night. Compared to the general population, people experiencing homelessness (PEH) sleep less and experience increased daytime fatigue. A common sleep disorder and treatable cause of morbidity and low quality of life is sleep apnea. High prevalence of chronic comorbid disorders of …

18 years of age All Phase N/A

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