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Toronto, Canada Clinical Trials

A listing of Toronto, Canada clinical trials actively recruiting patients volunteers.

Found 951 clinical trials

Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgaris

The goal of this observational study is to learn about the effects of a treatment that contains clindamycin phosphate, adapalene, and benzoyl peroxide in people with acne. The main questions the study aims to answer are: How satisfied are people with this treatment? How well do people follow the treatment …

12 years of age All Phase N/A
D Drew Taylor, MSc, PhD

Cryopreserved Hair Follicles for Disease and Cell Replacement

To explore the application of cells expanded from plucked hair follicles after collection, transport, and cryopreservation, in disease modeling and cell-based therapies.

18 - 80 years of age All Phase N/A
D Dr. Karisa Parkington, Ph.D.

Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study

The goal of this observational study is to learn about remote mental health monitoring technology for adults with treatment-resistant depression. The main question it aims to answer is: are digital mental health monitoring tools (an electronic data capture platform and wearable device (e.g., smartwatch or smart-ring)) feasible to implement alongside …

18 years of age All Phase N/A
J Jakob Kim

Emotion and Memory in Chronic Neuropathic Pain

Chronic pain affects one in four Canadians, leading to severe personal and societal costs. Over 70% of chronic pain patients report memory difficulties and fear having unexpected pain. Abnormalities in brain structures associated with emotion and memory, including the hippocampus and amygdala, can be affected by chronic pain. Understanding the …

35 - 60 years of age All Phase N/A
C Christina K. Uong

Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures

Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.

18 - 60 years of age All Phase N/A
Z Zujaja-Tul-Noor Zujaja-Tul-Noor, MSc

Weaning is Winning? (WeWin Study)

We propose a multicenter prospective study on pediatric patients with intestinal failure (IF) who weaned off parenteral nutrition (PN).

- 18 years of age All Phase N/A
L Laurent Brochard, MD

Pressure Muscle Index and Threshold of Over-assistance During Pressure Support Ventilation

Pressure support ventilation (PSV) is used to assist the breathing of the intubated patient with some pressure from the ventilator. This support aims at avoiding excessive inspiratory effort, while ensuring a certain degree of training of the patient's inspiratory muscle. Avoiding both minimal and excessive assistance is thus important for …

18 years of age All Phase N/A
J Julie Hallet, MD MSc FRCSC FSSO

Life Following Excision of Neuroendocrine Tumors

Neuroendocrine tumors (NETs), often seen as "chronic cancer" present a survival paradox with relatively prolonged patient survival despite active disease. Treatment strategies emphasize management over cure, integrating tumor control with quality of life (QOL) considerations. Surgery is a cornerstone of NET management but demands a careful balance between its potential …

18 years of age All Phase N/A
J Jayanta Chowdhury

MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery

This study seeks to define what constitutes an MCID and a PASS in patients undergoing a variety of elective major orthopedic surgery.

18 - 80 years of age All Phase N/A
Y Yishay Szekely, MD

NIVIA-Hemodynamics

This is an investigator-initiated, single-center, single-arm prospective study to compare non-invasive hemodynamic assessment using transthoracic echocardiography (TTE) and lung ultrasound (LUS) and hemodynamic assessment using PAC. Patients who have been hemodynamically assessed using PAC will be invited to participate. Each patient will undergo TTE and LUS immediately after first invasive …

18 years of age All Phase N/A

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