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Torento, Canada Clinical Trials

A listing of Torento, Canada clinical trials actively recruiting patients volunteers.

Found 1,008 clinical trials
D David Shultz, MD

Circulating Tumor DNA Collection From Patients With High Grade Gliomas

Improved outcomes for high-grade gliomas (HGG) require advances in our ability to monitor changes to tumour biology using non-surgical approaches. "Liquid biopsy" is a term used to describe a technique whereby tumour DNA, which has been shed off and then circulates through the blood stream, is detected and analyzed. Our …

18 - 100 years of age All Phase N/A
K Katharine Dunlop, PhD

Effect of Suicidality on Social Cognition

Major Depressive Disorder (MDD) is a very common illness that is usually treated with antidepressant medication. Depression can be caused by many things such as childhood experiences, genetics, and changes in the way the body and brain function. It is most likely caused by a combination of several of these …

18 - 65 years of age All Phase N/A
A Adriana Luk, M.D.

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

This large real-world international prospective registry will provide a unique opportunity to comprehensively understand the contemporary management, clinical course and short as well as long-term outcomes of all Cardiogenic Shock (CS) patients cared for at four high volume dedicated shock care centers. As the first true North American multicenter CS …

18 years of age All Phase N/A
K Kathy Han, MD

LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers

This is a correlative research project aimed at characterizing the T cell mediated immune responses to hepatocellular carcinoma (HCC), as well as Epstein-Barr virus (EBV)- and human papillomavirus (HPV)-related cancers. This study will enroll approximately 105 patients over 48 months. Of these 105 patients, 30 are EBV-related cancer, 45 are …

18 years of age All Phase N/A
D David Shultz, MD

FLT-PET / MRI Brain Mets

Brain metastasis (BrM) develops in approximately 40% of cancer patients. Stereotactic radiosurgery (SRS) is a form of radiotherapy that delivers high-dose per fraction to individual lesions that is commonly used to treat BrM. Radionecrosis (RN) is an adverse event that occurs in approximately 10 - 25% of patients 6 - …

18 - 100 years of age All Phase N/A
C Chelsi Major-Orfao, MEd

The Sunnybrook Type 2 Diabetes Study

The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from …

18 years of age All Phase N/A
M Mary Freeman

Anesthetics and Analgesics in Children

The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

- 17 years of age All Phase N/A
L Lili Senman

Accuracy of Community General Pediatrician Diagnosis of Autism Compared to a Multidisciplinary Team Assessment

The goals of this diagnostic study are to determine how accurate general pediatricians are in autism spectrum disorder (ASD) diagnostic assessment and which children might be best suited for this type of assessment. The investigators will also evaluate the use of a new virtual diagnostic tool, the Autism Assessment for …

- 64 years of age All Phase N/A
B Breton Line, BS

Complex Adult Deformity Surgery (CADS)

Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.

18 years of age All Phase N/A
D David Shultz, MD

Comparing SBRT to CRT in Patients With Spinal Metastases

This is a single institutional registry-based, prospective, observational study to describe radiation oncologists' decision making during evaluation of patients and to compare real-world outcomes of SBRT vs CRT. A registry-based trial involves observing the effect of something without manipulating it.

18 - 100 years of age All Phase N/A

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