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Torento, Canada Clinical Trials

A listing of Torento, Canada clinical trials actively recruiting patients volunteers.

Found 1,008 clinical trials
S Sharmini Atputharaj, MSc

Feasibility and Safety of a Combined Augmented Reality and Functional Electrical Stimulation System

Cervical spinal cord injury (cSCI) can result in substantial loss of upper-limb function, with associated socio-economic impact on affected individuals and the healthcare system. Evidence suggests that non-invasive neuromodulation such as functional electrical stimulation (FES) therapy can contribute to regaining upper-limb function, which is a top priority for this population. …

18 - 65 years of age All Phase 0
A Anna Kalleitner, RN

Greater Occipital Nerve Block for Spontaneous Intracranial Hypotension

Spontaneous Intracranial Hypotension (SIH) is a debilitating neurological disorder caused by a cerebrospinal fluid leak (CSF), with an estimated incidence of 5 per 100,000 persons per year, of which mostly women between the ages of 35 years and 55 years. The typical presentation is moderate-to-severe orthostatic headache and several other …

18 years of age All Phase N/A

A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis

The purpose of this study is to evaluate how well LY4256984 is tolerated and what side effects may occur in participants with sporadic amyotrophic lateral sclerosis (ALS). The study drug will be administered intrathecally (IT) into the spine. Blood tests will be performed to check how much LY4256984 gets into …

18 - 75 years of age All Phase 1
J Janice E Campbell, MSc

Effect of Prebiotic Sodas on Postprandial Levels of GLP-1, PYY, Transit Time and Satiety Levels: A Pilot Study

The main objective of this study is to evaluate the acute effects of prebiotic sodas on postprandial levels of glucagon-like peptide-1 (GLP-1), peptide YY (PYY), gastric emptying, and satiety levels in healthy adults.

18 - 60 years of age All Phase N/A
E Erica S Tsang, MD

Study of NABPLAGEM vs. Nab-Paclitaxel/Gemcitabine in BRCA1/2 or PALB2 Pancreatic Cancer

This study will compare two different regimens for patients with BRCA1/2 or PALB2 mutated metastatic pancreatic cancer after progression on first-line FOLFIRINOX.

18 years of age All Phase 2/3
D Dr. Michael Goldberg, MDM

Efficacy of SALI-10 Oral Probiotics in Experimental Gingivitis

Gingivitis is among the most prevalent oral diseases worldwide, affecting an estimated 50-90% of adults. It is a reversible condition primarily caused by microbial plaque accumulation on teeth and gingival surfaces, which triggers inflammation. Standard care emphasizes plaque reduction through oral hygiene, and research shows gingivitis can be reversed once …

18 - 70 years of age All Phase 2
I Ilona Bahinskaya, MSc, CCRP

Combined Light, ExVivo, and Antivirals for Recipients of Lungs From HBV Donors

The aim of the study is to show that transplantation of lungs from Hepatitis B-infected donors is safe when using EVLP with UV light inactivation plus antivirals

18 years of age All Phase 4
S Sabrina T. Barsky, Ph.D.

Validating IAAO for Muscle Outcomes

Consuming dietary protein stimulates whole-body and muscle protein synthesis, the latter of which is typically measured using invasive primed constant infusions of stable isotopes with concurrent muscle biopsies. Alternative non-invasive methodologies have been developed (namely the indicator amino acid oxidation (IAAO) technique) to estimate the impact of protein ingestion on …

18 - 35 years of age All Phase N/A
R Ryan Khan

Geriatric Acetabular fracTures: Open Reduction Internal Fixation Versus Replacement

Management of acetabular (hip) fractures in the geriatric population can be very challenging because of pre-existing medical comorbidities, pre-existing osteoporosis and increased risk of mortality. The two most common treatment options for acetabular fractures are either surgical fixation using plates and screws to hold the fractured pieces in the correct …

60 years of age All Phase N/A

The HEROES Trial: Hyperbaric Oxygen Therapy for Endometriosis-Related Pain

Endometriosis, is a condition where tissue from the uterus, called endometrium, grows outside of the uterus. This effects up to 10% of women, and can lead to long-lasting, moderate to severe pelvic pain, infertility and other symptoms. This can affect a woman's quality of life (including increased risk of depression …

18 years of age All Phase N/A

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