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St. John's, Canada Clinical Trials

A listing of St. John's, Canada clinical trials actively recruiting patients volunteers.

Found 55 clinical trials

ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS

The exploratory ELIOS study aims to assess the value of novel investigational Eye Movement Biomarkers (EMBs) in tracking disease-related changes among a real-world cohort of Canadian patients with active RRMS, within the context of disease-modifying treatment (i.e., ofatumumab). To that end, the study will use the patented investigational, Eye Tracking …

18 - 99 years of age All Phase 4
S Sheila N Garland

iCANSleep: Smartphone App-Based Insomnia Treatment for Cancer Survivors

The investigators will answer the question of whether treating insomnia using the mobile-app-based intervention of Cognitive Behavioural Therapy for Insomnia (CBT-I) for cancer survivors ("iCANSleep") can improve symptoms of insomnia in Canadian cancer survivors compared to a waitlist control group. The investigators will recruit 146 people with insomnia who have …

18 years of age All Phase N/A

Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of this study is to evaluate the pharmacokinetics, safety, and efficacy of povorcitinib in adolescent participants with moderate to severe hidradenitis suppurativa over a 54-week open-label treatment period.

12 - 17 years of age All Phase 2
C Candice E Crocker, PhD

Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis

Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in significant challenges for individuals and their families, including difficulties with thinking, relationships, and overall well-being. They …

16 - 30 years of age All Phase N/A

Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis

Canada reports some of the highest rates of cannabis use in our youth and young adult populations, among all the developed countries. Recent Health Canada surveys report that 27% of 16-19-year-olds and 32% of 20-24-year-olds have used cannabis in the past 30 days, with 16-24-year-olds showing the highest rates of …

18 - 25 years of age All Phase 4

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