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Nova Scotia, Canada Clinical Trials

A listing of Nova Scotia, Canada clinical trials actively recruiting patients volunteers.

Found 206 clinical trials
L Lutz Weise, MD

Correlation of Tractography and Motor Evoked Potentials in Deep Brain Stimulation

The goal is to establish another anatomical referencing system in order to achieve an even higher accuracy when implanting stimulation electrodes.

years of age All Phase N/A
A Alexandra McKinnon

The Canadian Maraviroc Randomized Controlled Trial To Augment Rehabilitation Outcomes After Stroke

The CAMAROS trial is a randomized controlled phase II trial analyzing the effect of coupling a C-C chemokine receptor 5 (CCR5) antagonist, Maraviroc (Celsentri), and exercise to improve both upper and lower extremity recovery after a stroke.

18 years of age All Phase 2
J Jennifer L Jones, MD

IBD Strong Peer2Peer for Self-Management of Psychological Distress

Psychological distress (PD) as a result of inflammatory bowel disease (IBD) is prevalent and associated with worse disease-related outcomes. IBD-associated psychological distress (IBD-PD) is particularly common at initial diagnosis, during disease flares, before surgery, and during transitions of care. Access to evidence-based, gold-standard psychological interventions and emotional support for IBD-PD …

18 - 99 years of age All Phase N/A

Brain Imaging Study on Biomarkers for Fibromyalgia

Drugs used for managing Fibromyalgia pain have not proven to be effective and pain continues to cost Canadians $60 billion a year without truly helping those who suffer. The study proposes to investigate the factors related to a person that can enhance or reduce the effectiveness of pain treatments in …

18 - 75 years of age All Phase N/A
D Darren Klugman, MD

Cord Clamping Among Neonates With Congenital Heart Disease

The goal of this clinical trial is to compare 2 different timepoints for clamping the umbilical cord at birth for term-born infants with a prenatal diagnosis of congenital heart disease (CHD). The main questions it aims to answer are: Does Delayed Cord Clamping at 120 seconds (DCC-120) or Delayed Cord …

37 - 42 years of age All Phase N/A

Silicone Taping for the Improvement of Abdominal Donor Site Scars

This study will look at silicone tape compared to the current no dressing standard at the investigators institution, to determine if silicone tape provides a significant improvement in post-abdominoplasty scar appearance. Silicone tape will be added to half of the abdominoplasty incision of patients undergoing abdominally-based breast reconstruction procedures two …

18 - 65 years of age All Phase N/A
J Jill Cumby, RN

Personalized Indications for CBT and Antidepressants in Treating Depression

Depression currently affects close to 2 million Canadians and is the leading cause of disability worldwide. Pharmacological treatments (antidepressant medication) and psychological treatments such as cognitive-behavioural therapy are available for depression, but the majority of those who receive treatment have an unsatisfactory response. On average, the combination of pharmacological and …

18 years of age All Phase 4
D David B. Clarke, MDCM, PhD, FRCSC, DABNS, FACS

90Yttrium Colloid for the Treatment of Cystic Sellar/Parasellar Tumors

There is no consensus in the literature on the best way to treat cystic lesions of the pituitary area. Patients who are symptomatic from these tumours are rare. The cystic form of tumours present special challenges since traditional treatment modalities (surgery and/or external radiation) are often not able to completely …

17 years of age All Phase 3
J Jill Cumby, RN

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

This is a study that will test a predictive biomarker algorithm based on results from a previous study. The goal of this study is to integrate clinical, imaging, EEG, and molecular data across 8 sites to predict treatment outcome for patients experiencing a major depressive episode (MDE).

18 - 65 years of age All Phase 4
P Philippe Guévremont, MDCM

Treatment Interrupts Depression Early

The TIDE project aims to establish personal indicators for initial treatment choice for youth with first episode depression. Specifically, 100 adolescents and young adults (age 12 to 25) with untreated major depressive disorder of recent onset will be randomly allocated in 1:1 ratio to one of two evidence-based regimens for …

12 - 25 years of age All Phase 2

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