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North York, Canada Clinical Trials

A listing of North York, Canada clinical trials actively recruiting patients volunteers.

Found 1,045 clinical trials
K Kristi Downey, MSc

OBS-QoR-10 in Patients With and Without Postpartum Hemorrhage

Postpartum hemorrhage (PPH) remains a leading cause of maternal death and morbidity. Moreover, it also contributes to psychological trauma such as depression and post-traumatic stress disorder. The American College of Obstetrics and Gynecology (ACOG) and the Society for Maternal Fetal Medicine (SMFM) defines this morbidity as an unintended outcome in …

18 years of age Female Phase N/A
C Celeste Yu

Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!)

Patients who have undergone curative treatment may be at risk of relapse. This study will collect, annotate, and sequence biospecimens (blood, stool, and tissue) from patients across different tumor types to detect molecular residual disease (MRD) before metastases become radiographically or clinically detectable. This will allow for early cancer interception, …

18 years of age All Phase N/A
L Linda Karnay

Using ctDNA to Detect Minimal Residual Disease After Lung Cancer Resection

ctDNALung-Detect is an investigator-initiated single arm, multi-institution study designed to assess the ctDNA detection rate and its association with Relapse Free Survival (RFS) in operable stage T1-T4 (T3,T4 multifocal) N0M0 non-small cell lung cancer (NSCLC) patients.

18 years of age All Phase N/A
G Gabriel Altit, Co-Site Lead

Early-life MRI Biomarkers of Longer-term Respiratory Morbidity in Infants Born Extremely Preterm (EMBLEM)

Bronchopulmonary dysplasia (BPD) is a common, major complication of premature birth, associated with developmental and health consequences that continue into adulthood. Prediction of who will have these problems is challenging using traditional definitions of disease. It is believed that underdevelopment and injury occur in both lung tissue and the blood …

35 - 21 years of age All Phase N/A
S Shahid Husain, MD,MS

Assessment of Volatile Organic Compounds (VOC) for the Diagnosis of Invasive Aspergillosis (IA) in Lung Transplant Recipients

Prospective observational pilot study to evaluate the utility of breath VOCs to detect invasive aspergillosis in lung transplant recipients that are suspected of invasive fungal disease (IFD).

18 years of age All Phase N/A
R Reva Persaud

Looking for Asymptomatic Mpox in a Population at High Risk

Mpox is caused by a virus that can be spread through touching the affected skin of someone who has the infection, touching sheets or clothes that has been used by someone with the infection, or breathing in particles of virus from someone who has the infection. Mpox infection can cause …

years of age Male Phase N/A
A Amit Oza, M.D.

Umbrella Study for Single Patient Treatments in Oncology

The purpose of this study is to collect data on how advanced and rare cancers respond to biomarker-based treatments.

18 years of age All Phase N/A
C Carrie Lindsay

Radiation OmisSion in PAtients With CLinically Node Negative Breast Cancer Undergoing Lumpectomy

To de-escalate radiation therapy in women with breast cancer.

50 years of age Female Phase N/A
G Gregory J Czarnota, PhD, MD

Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

years of age All Phase N/A

Respiratory Muscle Structure and Function in Mechanically Ventilated Patients and Long-term Outcomes

Air is normally pumped in and out of the lungs by the muscles that contribute to inhalation and exhalation, called the respiratory muscles. The abdominal muscles help by forcing air out of your lungs during exhalation; whereas the diaphragm, the main muscle used for breathing, contracts to get air into …

18 years of age All Phase N/A

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