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North Vancouver, Canada Clinical Trials

A listing of North Vancouver, Canada clinical trials actively recruiting patients volunteers.

Found 467 clinical trials
L Levina Ira

Montbretin Clinical Trial in Healthy Volunteers and Type 2 Diabetics

The goal of this clinical trial is to test the investigational product, Montbretin A (MbA) in either individuals with type 2 diabetes (T2D) or healthy participants. The main questions it aims to answer are: Safety of MbA Whether MbA has less side effects in comparison to other medications used to …

19 - 65 years of age All Phase 1
S Sara Mahdavi, PhD

Optimizing Prostate Cancer Treatment in Men With Advanced Local Disease

Multi-modality therapy that includes a brachytherapy implant improves outcomes in locally advanced prostate cancer when compared to other radiation-based treatments, but is also associated with more adverse side effects. The goal of the OPTiMAL trial is to reduce these side effects by using advanced imaging and biopsy techniques to locate …

18 years of age Male Phase N/A
T Tina Zhang, MD

A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor.

This study is a phase III multi-institutional randomized trial. Patients will be randomized in a 1:2 ratio between current standard of care treatment (Arm 1) vs. standard of care treatment + SABR (Arm 2) to sites of known disease. Patients will be stratified by two of the strongest prognostic factors, …

18 years of age All Phase 3
S Site Public Contact

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiation therapy with hippocampal …

18 years of age All Phase 3
S Stefan Lang, MD PhD FRCSC

Theta Deep Brain Stimulation for Cognitive Enhancement in Parkinson's Disease

Cognitive impairment is common in Parkinson's disease. A recent study demonstrated 40% of people with PD suffer from mild cognitive impairment and \> 80% of patients develop dementia after a disease duration of 20 years. Cognitive impairment significantly impairs quality of life and has limited treatment options. While the pathophysiology …

18 - 80 years of age All Phase N/A

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

The purpose of this study is to evaluate the safety, tolerability, and efficacy of escalating doses of BMS-986463 in participants with select advanced malignant tumors.

18 years of age All Phase 1
K Kate Hunker, B.A.

Cognitive-Behavioural Couple Therapy for Sexual Interest/Arousal Disorder

Sexual health is a fundamental aspect of quality of life; a satisfying sexual relationship is linked to better physical, psychological, and relationship health and well-being. In fact, people who maintain a satisfying, active sex life over time live longer than those who report lower sexual frequency and satisfaction. Yet problems …

18 years of age All Phase N/A
P Peter Subrt

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

A companion platform trial to test novel targeted agents based on the patient's tumor profile.

- 21 years of age All Phase 1/2
T Tiffany Reeve, MSc

Stillbirth Risk Identification Using Multiparametric Ultrasound

The goal of this observational study is to identify a novel biomarker for stillbirth. Specifically the aim is to predict perinatal hypoxia using quantitative ultrasound from the placenta (QUS-P) between 35 and 37 weeks gestation.

19 years of age Female Phase N/A
A Alexandra McKinnon

Optimizing Recruitment to Drive Equitable Research Opportunity in Stroke Rehabilitation Trials in Canada

Stroke is a major health issue in Canada. Stroke affects over 400,000 Canadians, and this number is expected to nearly double by 2038. Research studies in stroke recovery can help us better understand effective rehabilitation treatments and help reduce the burden of stroke. Some groups of people however are commonly …

18 years of age All Phase N/A

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