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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,315 clinical trials
S Stephanie A Torres, PhD

Pilot Testing of a Structural Racism Intervention for Immigrant Latinx Families

The purpose of this study is to evaluate a new, community-based, group intervention called FIESTA (Familias Inmigrantes Empoderándose contra eStrés Tomando Acción) to understand how well it helps Latinx immigrant families deal with the impact of stress due to structural racism. Structural racism is defined as the policies, practices, and …

14 - 17 years of age All Phase N/A
S Shalaka Joshi, MS, MCh

A Prospective Evaluation of the Peri-operative Hypoxia in Breast Cancer

To understand the effects induced by acute hypoxia that sets in during surgery in breast cancer. To study this, clinical samples (Tumor biopsies) will be obtained during the surgery after partial devascularisation (sample B) and stored for future genomic and proteonomic evaluations.

18 years of age Female Phase N/A
A Andersson, Prof.

High-intensity Training in Patients With Spondyloarthritis: a Randomized Controlled Trial

Project summary Background: For people diagnosed with a spondyloarthritis (SpA) e.g. ankylosing spondylitis or undifferentiated spondyloarthritis, physical activity and exercise are important components in the self-management. Exercise, in addition to physical and mental symptoms related to the disease can easily feel overwhelming to exercise, and low adherence may result. By …

18 - 67 years of age All Phase N/A
K Kuaile Zhao

A Study of IO Plus Radiotherapy in Patients With Advanced ESCC.

This study is a single-arm, prospective, phase II trial for patients with metastatic esophageal squamous cell carcinoma (ESCC) who received immunotherapy plus chemotherapy as the first-line treatment. The aim of the study is to determine if intervening with combined local therapy and immunotherapy and chemotherapy in patients with ESCC led …

18 - 80 years of age All Phase N/A
A Annette Kinsella, RN, CCRC

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

This feasibility trial studies how well daratumumab in combination with dose-adjusted etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride (DA-EPOCH) works in treating patients with newly diagnosed stage I-IV plasmablastic lymphoma. Plasmablastic lymphoma cells have high levels of a protein called CD38. Daratumumab is a monoclonal antibody that specifically targets …

18 years of age All Phase 0
B Bo Zheng, Dr

A Clinical Study of Fundus OCTA for the Identification of CMD

Coronary microvascular dysfunction (CMD) carries an increased risk of adverse cardiovascular clinical outcomes. The association between fundus microcirculation changes and coronary microcirculation is not well understood. Optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) is a new type of optical diagnostic imaging technology for non-invasive detection, which can …

18 years of age All Phase N/A
V Virend Somers, MD, Ph.D

A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

Studies show that sleep apnea increases the risk of cardiovascular disease and is associated with obesity. However, it is unclear how sleep apnea affects fat tissue. Studies have shown that fat tissue is likely involved in developing cardiovascular disease. The purpose of this study is to see how sleep apnea …

18 - 60 years of age All Phase N/A
J Jette Lautrup Frederiksen, Prof, MD

Indole-3-PROpionic Acid Clinical Trials - a Pilot Study Part 2

The goal of this trial is to investigate the biological effects of oral supplementation with indole-3-propionic acid (IPA) taken twice daily in healthy adults. The main scientific questions are: Does supplementation with IPA increase the abundance of regulatory T cells in the blood? Regulatory T cells are believed to play …

18 - 65 years of age All Phase N/A
L Lynne Bell

Investigating the Effects of a Haskap Berry Supplement on Cognitive Health

This study aims to investigate the postprandial (2h) and longer term (4 week) effects of a haskap berry supplement on cognitive, vascular, and metabolic function in healthy ageing adults aged 50+.

50 years of age All Phase N/A
J Jaya (Mini) Gill

A Study to Examine Anktiva for the Treatment of COVID-19.

This study will examine the safety and effectiveness of Anktiva in treating patients with Long COVID-19 which is defined as persistent symptoms of a COVID-19 infection that remain after the infection is over.

18 - 70 years of age All Phase 2

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