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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 10,489 clinical trials

A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

The purpose of this study is to evaluate the safety and efficacy of solbinsiran in lowering triglycerides and other lipid measures compared to placebo in participants with severe hypertriglyceridemia. Participants will receive two subcutaneous injections.

18 years of age All Phase 2

A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis

The aim of this study is to evaluate the safety of F8IL10 when administered by intra-articular injection and to determine the maximum tolerated dose (MTD) in order to establish the recommended dose (RD) in patients with Reumatoid Arthritis.

18 - 80 years of age All Phase 1
A Audrey Jullian

E-CANE: a National Program of Remote Health Education Workshops

About 2000 adolescents and young adults (AYA) are diagnosed with cancer each year in France. This period of life is marked by a maturation and transition phase in various areas (psychological, physical, sexual, socio-professional...). Cancer occurrence has a very particular impact. AYAs diagnosed and treated for cancer have specific medical …

15 - 25 years of age All Phase N/A

A Study of Avoralstat In Participants With Diabetic Macular Edema

The goal of this study is to assess the safety and therapeutic potential of a single dose of avoralstat in adult participants with DME.

18 years of age All Phase 1
A Andrea De la Torre

Practice-Based Evidence in Psychotherapy: A Multicentric Study From Ecuador

The goal of this observational study is to learn about the progress and outcomes of clients receiving psychotherapy for common mental health problems in Ecuador. The main questions it aims to answer are: How much do clients' psychological distress typically change during the course of their psychotherapy? What factors are …

11 years of age All Phase N/A
J Joshua Alexander, Ph.D.

Evaluating a Deep Neural Noise-Reduction Algorithm for Hearing Aids

This study is designed to understand how different hearing-aid noise-reduction technologies affect a listener's ability to hear speech in noisy environments. Participants will listen to speech at several background-noise levels while trying different processing settings. By comparing performance across these conditions, the study aims to identify which types of noise …

18 years of age All Phase N/A
A Adicet Clinical Trials

A Phase 1 Study of ADI-001 in Rheumatoid Arthritis

ADI-001-106 is a phase 1 study of ADI-001 with a randomized, single-blind, parallel group design to compare two different LD regimens in subjects with treatment-refractory RA. The study will consist of different periods including screening, LD, treatment, and follow-up

18 - 80 years of age All Phase 1

A Phase 1 Study of CLYM116 in Normal Healthy Volunteers

This Phase 1, first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of CLYM116 in healthy volunteers.

18 - 60 years of age All Phase 1
N Ning Li

A Study of CSCJC3456 in Patients With Advanced Malignant Tumors

This study is a multicenter, open phase I clinical study of dose escalation, cohort expansion study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of CSCJC3456 in patients with advanced malignant solid tumors.

18 - 75 years of age All Phase 1
S SHEN LIN

A Study of MRG007 in Patients With Advanced Solid Tumors

This is an open-label, multi-center, phase I/II study to evaluate the safety, efficacy, and pharmacokinetics of MRG007 in patients with unresectable locally advanced and metastatic solid tumors.

18 - 75 years of age All Phase 1/2

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