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London, Canada Clinical Trials

A listing of London, Canada clinical trials actively recruiting patients volunteers.

Found 245 clinical trials
E Elizabeth A Osuch, MD

Exploring Novel Uses of Microbiota Therapy for Managing the Side Effects of Psychiatric Pharmaceutical Interventions

To determine the feasibility of whether the addition of key prebiotics administered orally can mitigate some of the most problematic side-effects of the most common psychiatric medications - weight gain and metabolic abnormalities caused by some antidepressants, mood stabilizers and antipsychotics. In the initial part of the study, we aim …

16 - 25 years of age All Phase 1

Anxiolysis for Laceration Repair in Children

This is a 3-arm adaptive clinical trial to the optimal light sedative for reducing distress during laceration repair in children. The investigators will compare intranasal (IN) dexmedetomidine, IN midazolam, and nitrous oxide (N20). The primary outcome is the Observational Scale of Behavioral Distress - Revised (OSBD-R).

2 - 12 years of age All Phase 3

Video Stylet vs. Flexible Bronchoscopy for C-Spine

Comparison of cervical spine movement during intubation with the C-MAC Video Stylet to Flexible Bronchoscopy

18 - 80 years of age All Phase N/A
K Kaydee Connors

[18F] PSMA-1007 PET/CT in Metastatic Clear Cell Renal Cell Carcinoma

Staging of kidney cancer is primarily achieved by computerized tomography (CT) scans or magnetic resonance imaging (MRI). If a patient is found to have limited metastatic disease, surgical removal or radiation therapy could be considered in order to control the majority of the disease. However, if metastases are more widespread, …

18 years of age All Phase N/A
R Rahul Nayak

Prevention of Post Operative Urinary Retention After Thoracic Surgery Trial

The objectives of this study are to determine the feasibility of conducting a full-scale randomized control trial comparing the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention in people undergoing elective thoracic surgery.

40 years of age All Phase 2

Single vs. Dual Implant Fixation for Distal Femur Fractures in Older or Compromised Adults

The goal of this clinical trial is to assess the feasibility of conducting a larger study comparing single implant fixation (SIF) and dual implant fixation (DIF) for treating distal femur fractures (DFF) in older or compromised adults. It will also evaluate the safety and effectiveness of these treatments. The main …

18 - 100 years of age All Phase N/A
E Erin Lewis, PhD

A Clinical Trial Investigating the Efficacy and Safety of a Lipase Thera-blend and a Lipase Thera-blend + Tributyrin on Memory in Healthy Adults With Self-reported Memory Problems

The goal of this clinical trial is to investigate the efficacy and safety of Lipase Thera-blend and Lipase Thera-blend + tributyrin on memory in healthy adults with self-reported memory problems. The main question[s] it aims to answer [is/are]: Does of Lipase Thera-blend improve memory in healthy adults? Does Lipase Thera-blend …

30 - 79 years of age All Phase N/A

Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury

The goal of this study is to determine what happens to the heart muscle contraction when people cycle before their hemodialysis treatment. Will pre-dialysis exercise protect the heart from a decrease in pumping of the heart muscle (called stunning) that can happen during hemodialysis. We will study whether pre-dialysis exercise …

18 - 79 years of age All Phase N/A

Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases

This study is being done to answer the following question: Is Stereotactic Body Radiation Therapy or SBRT (a form of radiation therapy which can deliver high doses of radiation to the specific painful area of the body most affected by cancer, while keeping the radiation beams away from the healthy …

18 years of age All Phase 3
E Erin Lewis, PhD

A Clinical Trial to Investigate the Effect of Pollen Extracts on Menopausal Symptoms in Healthy Women.

The goal of this study is to investigate the effect of pollen extracts on menopausal symptoms in healthy women The main question it aims to answer is: What is the difference in change in severity of menopausal symptoms as assessed by the total Menopause Rating Scale (MRS) score from baseline …

45 - 65 years of age Female Phase 2

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