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London, Canada Clinical Trials

A listing of London, Canada clinical trials actively recruiting patients volunteers.

Found 239 clinical trials

Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury

The goal of this study is to determine what happens to the heart muscle contraction when people cycle before their hemodialysis treatment. Will pre-dialysis exercise protect the heart from a decrease in pumping of the heart muscle (called stunning) that can happen during hemodialysis. We will study whether pre-dialysis exercise …

18 - 79 years of age All Phase N/A
R Rahul Nayak

Prevention of Post Operative Urinary Retention After Thoracic Surgery Trial

The objectives of this study are to determine the feasibility of conducting a full-scale randomized control trial comparing the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention in people undergoing elective thoracic surgery.

40 years of age All Phase 2
C Charlene S Carlo

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

This study is a placebo-controlled Phase I study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide (ASO) AMX0114 in adult participants with amyotrophic lateral sclerosis (ALS).

18 years of age All Phase 1
D David Crowley, MD

Effects of Bacillus Coagulans SNZ 1969 on Immune Health in Healthy School-aged Children

The goal of this clinical trial is to investigate the safety and efficacy of Bacillus coagulans SNZ 1969 on immune health in healthy school-aged children in terms of reduction of respiratory symptoms, gastrointestinal symptoms, immunoglobulins, immune biomarkers and fecal microbiome changes. The current study will examine the efficacy of Bacillus …

6 - 12 years of age All Phase N/A
D David Crowley, MD

A Clinical Trial to Assess the Efficacy of a Single-dose of AlphaWave® L-Theanine on Cognitive Function in Healthy Adults With Moderate Stress

The goal of this clinical trial is to to assess the efficacy AlphaWave® L-Theanine on mental acuity/cognitive function and stress relief in healthy adults with moderate stress. The main question it aims to answer is: Is there a difference in change in mental acuity from pre- to post-dose between AlphaWave® …

18 - 60 years of age All Phase N/A
D David Palma, MD

Stereotactic Post-operative Radiotherapy for Intraparotid Metastatic Cutaneous Squamous Cell Carcinoma

The purpose of this study is to compare the effectiveness and side effects of stereotactic radiotherapy (5 sessions) against conventional (standard) radiotherapy (20-30 sessions) for the treatment of skin cancer involving the head and neck after surgical resection. Stereotactic radiotherapy works in the same way that conventional (standard) radiotherapy does …

18 years of age All Phase N/A
T Typhaine Gris, PhD

A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer

This is a phase II randomized controlled clinical trial comparing standard induction BCG versus bicalutamide and standard induction BCG among patients with non-muscle invasive bladder cancer.

18 years of age Male Phase 2
Z Zahra Kassam, MD

Gadoxetate Abbreviated MRI in Metastatic Colorectal Cancer

After a patient is diagnosed with colon cancer, they receive a CT of the chest, abdomen, and pelvis to see if the cancer has spread (metastasized) to other parts of the body. A common site for the cancer to spread to is the liver. If an abnormality is seen in …

18 years of age All Phase N/A
G Grace E Parraga, PhD

Xenon-129 Magnetic Resonance Imaging of Healthy Subjects: Hardware and Software Development and Reproducibility

Healthy volunteers aged 18-85 will undergo hyperpolarized 129-Xe MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.

18 - 85 years of age All Phase N/A

Video Stylet vs. Flexible Bronchoscopy for C-Spine

Comparison of cervical spine movement during intubation with the C-MAC Video Stylet to Flexible Bronchoscopy

18 - 80 years of age All Phase N/A

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