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London, Canada Clinical Trials

A listing of London, Canada clinical trials actively recruiting patients volunteers.

Found 245 clinical trials

Early NMES and Mirror Therapy Interventions During Immobilization of Distal Radius Fracture

Current practice for distal radius fractures is to begin rehabilitation after immobilization to remediate the resulting impairments. Neuromuscular electrical stimulation and mirror therapy are strategies that integrate neurological and musculoskeletal activation, that may be beneficial for mitigating the resulting impairments if applied during immobilization. The study aim is to determine …

18 - 80 years of age All Phase N/A
M Maha El-shimy

Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

This study will examine the effectiveness of administering adalimumab as a treatment for patients in the early stages of steroid-dependent immune checkpoint Inhibitor associated inflammatory arthritis (ir-IA). Adalimumab (ADA) is a TNF inhibitor (TNFi) that is well established as a standard of care treatment for numerous types of inflammatory arthritis. …

18 years of age All Phase 2
J John G Lenehan, MD, FRCPC

CHemotherapy and Stool Transplant in PDAC (CHASe-PDAC)

To confirm the safety of combining oral fecal microbiota transplantation (FMT) with gemcitabine and nab-paclitaxel chemotherapy as first line treatment in patients with unresectable or metastatic pancreatic ductal adenocarcinoma.

18 years of age All Phase 1
D Deb Lewis

Patient Reported Outcomes Targeting Early Chest Tube Removal (PROTECTR) Study

This study is a single centre, prospective clinical trial evaluating the safety and feasibility of implementing a same day chest tube removal protocol in patients undergoing Video Assisted Thoracic Surgery (VATS) anatomical pulmonary surgery.

18 years of age All Phase N/A
M Marc Moulin

A Clinical Trial to Investigate the Efficacy of Bragg Apple Cider Vinegar on Blood Glucose Control in a Healthy Adult Population

The goal of this clinical study is to investigate the efficacy of a Bragg Apple Cider Vinegar (ACV) liquid on postprandial glucose (PPG) excursion compared to a placebo following a standardized acute carbohydrate load. The main question it aims to answer is: Is there a difference in the incremental area …

20 - 50 years of age All Phase N/A
A Abhijit Biswas, MD

QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS

Video assisted thoracic surgery (VATS) has emerged as standard of care for majority of thoracic surgeries. It is less invasive compared to thoracotomy and is associated with improved perioperative outcomes [1-3]. Good perioperative analgesia after thoracic surgery will enable pulmonary toilet, early chest physiotherapy and mobilisation, [4,5,6]. Thirty-day hospital visits …

18 years of age All Phase N/A
A Arden Lawson, BMSc

Fecal Microbial Transplantation for Rheumatoid Arthritis Trial

This clinical trial will investigate the effects of capsules containing stool from healthy donors, called fecal microbial transplant (FMT), in rheumatoid arthritis patients.

18 years of age All Phase N/A
S Siobhan Scharbun, BSc

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of healthcare costs in Canada, and its pain is a major reason people see doctors. The pain is linked to …

45 years of age All Phase N/A
J Jarrin Penny, RN

An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL

Investigators know that many patients who are on dialysis suffer from burden of unwanted symptoms, which can affect quality of life. The understanding and treatment of symptom burden by healthcare providers is limited and should be recognized as a high priority in the care of the dialysis population. In this …

18 years of age All Phase N/A
A Angelina Dhanoa

Study of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients

This study will evaluate efficacy and tolerability of iberdomide, bortezomib, dexamethasone and isatuximab on demand administered in combination.

65 years of age All Phase 2

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