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Laval, Canada Clinical Trials

A listing of Laval, Canada clinical trials actively recruiting patients volunteers.

Found 366 clinical trials
J Josiane Lafleur

TRIple Negative Breast Cancer Markers In Liquid Biopsies Using Artificial Intelligence

Triple negative breast cancer (TNBC) is the most aggressive of breast cancers and it is usually treated with chemotherapy even before surgery. In many cases, the chemotherapy completely "melts" the tumor and these patients do well. When the tumor is not eliminated by the chemotherapy, the patient receive more chemotherapy …

18 years of age All Phase N/A
J Jeannette Bere, BSc

The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic Conditions

People with rheumatic conditions often take many medications, but more pills can increase the risk of side effects, especially in older adults. Some drugs (such as those intended to help pain or sleep) may cause more harm than good in the long term, and others may simply be no longer …

60 years of age All Phase N/A

The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 Diabetes

Type 1 diabetes is an autoimmune health condition that requires daily injections of insulin. Insulin allows the body to use energy from carbohydrates in food. Disordered eating behaviours, like restricting food intake to lose body weight, are more common in women and people with type 1 diabetes, compared to those …

12 years of age All Phase N/A

Daridorexant for Alzheimer Disease Prevention

This study will evaluate whether daridorexant, a DORA sleep medication, can support brain health by promoting the clearance of proteins linked to the development and progression of Alzheimer's disease. The trial is preventive and is open to participants who do not have Alzheimer's disease dementia, regardless of whether or not …

50 - 90 years of age All Phase 2
M Mark A Ware, MD

Music as an Adjunct to Ketamine Therapy for Chronic Pain

Intravenous (IV) ketamine is a treatment option for patients with chronic pain that does not respond to standard therapies, primarily working by blocking NMDA receptors in the brain. Beyond pain relief, ketamine can produce dissociative sensations, classifying it as an atypical psychedelic or mind-altering drug, and may enable patients to …

18 years of age All Phase N/A
J Julie Leclerc

Cognitive-psychophysiological Treatment for Tics in Young People With Tourette's Syndrome With or Without Biofeedback

The goal of this clinical trial is to compare the effectiveness of CoPs therapy with or without the therapeutic component of biofeedback in treating tics in Tourette Syndrome with emerging young adults. Hypotheses The CoPs+Biofeedback treatment will improve the severity of tics (YGTSS) and the Clinical Global Impression, surpassing the …

14 - 21 years of age All Phase N/A
M Manon de Raad

A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers

Men with prostate cancer and their family caregivers face many physical and emotional challenges from the cancer itself and its treatment(s), which often lead to high anxiety. The pandemic has highlighted the importance of protecting our physical and mental health, and the complex responsibilities that caregivers have in supporting their …

18 years of age All Phase N/A

A Phase 1 Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers

The purpose of this study is to evaluate the safety and tolerability of single ascending doses of ALN-4324 in healthy volunteers and to characterize the single-dose PK of ALN-4324.

18 - 65 years of age All Phase 1
T Tania Janaudis-Ferreira, PhD

Inspiratory Muscle Training in Lung Transplant Candidates

Recovery after lung transplantation (LTx) may be complicated by prolonged mechanical ventilation (MV) and protracted intensive care unit (ICU) stay leading to immobilization and impaired health-related quality of life (HRQoL). In the critical care setting, diaphragm atrophy and weakness have been associated with difficulty weaning from MV, increased risk for …

18 years of age All Phase N/A
A Alex Moore, MD

A Study of Pain Reduction After Pulmonary Resection by VATS, RATS-OTC, and Hybrid RATS.

Pulmonary resections are key in treating lung neoplasms, with techniques adapted to tumor size and location. Minimally invasive approaches like VATS have replaced open thoracotomy, but intercostal trocar placement can lead to nerve injury and chronic pain. Robotic-assisted thoracic surgery (RATS) is usually done via a transthoracic (RATS-TT) approach using …

18 years of age All Phase N/A

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