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Halifax, Canada Clinical Trials

A listing of Halifax, Canada clinical trials actively recruiting patients volunteers.

Found 206 clinical trials

Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients

A focus of research for youth and Emerging Adults with early phase psychosis (EPP) has been cannabis use. However, this focus has led to overlooking the possible negative influence of another legal recreational drug, alcohol. Previous studies our research group has done have demonstrated that over use of alcohol reduces …

16 - 35 years of age All Phase N/A
S Scott Grandy, MD

Prehabilitation for Ovarian Cancer Patients

Individuals with ovarian cancer have very poor survival rates. This is because the cancer is not usually detected until it has reached advanced stages. How long an individual survives also is determined by the cancer treatment they receive. Although there are best treatment practices to improve survival, some women have …

18 years of age Female Phase N/A

Evaluating the Effect of Intravenous Dexamethasone on the Duration of Spinal Anesthesia After Cesarean Delivery

The goal of this clinical trial is to determine the effects of intravenous (IV) dexamethasone on spinal anesthesia in healthy women having an elective Cesarean delivery (CD) at the IWK Health Centre. The main questions it aims to answer are: What effect does IV dexamethasone have on the resolution of …

18 years of age Female Phase 4
D Devan Pancura, MSc

Lower Trapezius Transfer vs Bridging Reconstruction

The goal of this clinical trial is to compare the bridging reconstruction technique vs the lower trapezius tendon transfer in patients with massive irreparable rotator cuff tears. The main questions it aims to answer are: comparing the outcomes of the two surgical techniques (BRR with an acellular human dermal allograft …

18 years of age All Phase N/A
S Shanna C Trenaman

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

Insomnia is a highly common, chronic disorder that is distressful for the patient but also for caregivers and can give rise to a heavy burden on the healthcare team. Sleeping aids like benzodiazepines and other sedatives (e.g., zolpidem, zopiclone) have been widely used to help treat insomnia. However, sleeping aids …

years of age All Phase 4
G Gayle Nickol

Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma

The goal of this prospective clinical trial is to investigate the safety and efficacy of ST-02 (mucoadhesive gemcitabine suspension for pyelocaliceal instillation) to treat Upper Tract Urothelial Carcinoma (UTUC) in participants who have a low-grade tumor. The main questions this study aims to answer are: Can ST-02 effectively eradicate UTUC …

18 years of age All Phase 2/3

Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma

This study is being done to answer the following question: Can the chance of gastroesophageal cancer growing or spreading be lowered by adding a drug called zanidatamab to the usual combination of drugs? We are doing this study because we want to find out if this approach is better or …

18 years of age All Phase 2
H Hannah Dahn, MD

Brass Mesh Bolus in Rotational Post-Mastectomy Radiation Therapy

The hypothesis is that the daily use of brass mesh bolus achieves a comparable dose to every-other-day use of Superflab bolus (current standard of care) in chest wall post-mastectomy patients treated with rotational 6 MV photon delivery.

years of age All Phase N/A
J Janet Slaunwhite

CONCEPTT Kids International Neurodevelopmental Outcomes Among Offspring of Women With Type 1 Diabetes

Neurodevelopmental Outcomes among Offspring of women with Type 1 Diabetes: A Follow up Study of the CONCEPTT Randomized Control Trial (CONCEPTT Kids International). An international, multicentre prospective cohort study of child and mother pairs. The potential number of recruits is 225 and the main inclusion criteria is child's mother who …

6 years of age All Phase N/A
M Molly Williams, MBBS

Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

The efficacy of treatment with metformin for promoting cognitive recovery and brain growth in children/adolescents treated for a brain tumour will be investigated in a multi-site Phase III randomized double-blind placebo-controlled parallel arm superiority trial. Specifically, in children/adolescents aged 7 years to 21 years and 11 months who have completed …

7 - 21 years of age All Phase 3

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