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Greenfield Park, Canada Clinical Trials

A listing of Greenfield Park, Canada clinical trials actively recruiting patients volunteers.

Found 569 clinical trials
M Mireille Joussemet, Ph.D.

Improving Preschoolers' Mental Health: A RCT Assessing Two Parenting Programs

The goal of this randomized control trial (RCT) is to assess the superiority of the How-to Parenting Program in improving autonomy support and preschoolers' mental health (i.e., decreases externalizing problems) among vulnerable families. The main question it aims to answer is: Can teaching concrete parenting skills that target empirically-based parenting …

18 years of age All Phase N/A
M Melissa Huynh, MD

A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer

This is a phase II randomized controlled clinical trial comparing standard induction BCG versus bicalutamide and standard induction BCG among patients with non-muscle invasive bladder cancer.

18 years of age Male Phase 2

A Study to Evaluate ALN-6400 in Adult Healthy Volunteers

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of ALN-6400 in healthy volunteers.

18 - 65 years of age All Phase 1

A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors

The purpose of this study is to assess the safety and tolerability of BMS-986484 administered alone, in combination with nivolumab in participants with advanced/metastatic solid tumors including non-small cell lung cancer (NSCLC), microsatellite stable (MSS) colorectal carcinoma (CRC), pancreatic ductal adenocarcinoma (PDAC), gastric/gastroesophageal junction adenocarcinoma (G/GEJC), and squamous cell carcinoma …

18 years of age All Phase 1
H Helene Brown, RN. B.Sc.

Patient SELF-management With HemodynamIc Monitoring: Virtual Heart Failure Clinic and Outcomes

To demonstrate that a virtual Heart Failure Clinic (HFC) based on patient self-management using Pulmonary Artery Pressure (PAP) monitoring is superior to usual care of HFC, leads to decreased: hospital admissions for heart failure (HF), emergency department consultation and/or unplanned intravenous heart failure therapy and cardiovascular death, compared to a …

18 years of age All Phase N/A

Single and Multiple Ascending Oral Doses of Avenanthramide

Avenanthramides (AVA) are di-phenolic compounds found only in oats and are of interest due to suggested bioactivities, including antioxidant and anti-inflammatory effects in vitro and in vivo. Published data suggests that polyphenols can work as modifiers of signal transduction pathways to elicit their beneficial effects. These natural compounds express anti-inflammatory …

18 - 60 years of age All Phase 1/2
V Véronique Daneault, M.Sc., Ph.D.

The Effects of Lemborexant on the Ability to Sleep During Daytime

This study aim to evaluate whether a dose of 5 mg of lemborexant, as compared to a placebo, may improve daytime recovery sleep, without producing lingering sleepiness during wakefulness, using a 3-day simulated night shift protocol in the lab under constant monitoring.

30 - 60 years of age All Phase 2
J Julie Fleury

Real-life Implementation of an AI-based Optical Diagnosis

This is a prospective study that is the first to implement resect and discard and diagnose and leave strategies in real-time practice using stringent documentation and adjudication by 2 expert endoscopists as the gold standard. Therefore, this study mainly aims to evaluate the agreement between (CADx) assisted optical diagnosis and …

45 - 80 years of age All Phase N/A

Galderma HA Filler Migration

Soft tissue filler injections continue to grow in popularity as a method of facial rejuvenation, including volume restoration and contour enhancement. Many different hyaluronic acid (HA)-based fillers are available on the market and differ in terms of their physical and chemical properties, which results in families of fillers (e.g., Non-Animal …

18 years of age All Phase N/A
C Caroline Girard

Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT

The Thermedical Ablation System and Durablate catheter is indicated for use in patients with recurrent, sustained, monomorphic ventricular tachycardia (SMVT) refractory to drug therapy and conventional (approved) catheter ablation. Subjects with recurrent, SMVT refractory to drug therapy and conventional catheter ablation who are not eligible for, or will not likely …

18 years of age All Phase N/A

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