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Edmonton, Canada Clinical Trials

A listing of Edmonton, Canada clinical trials actively recruiting patients volunteers.

Found 425 clinical trials
D Darren Klugman, MD

Cord Clamping Among Neonates With Congenital Heart Disease

The goal of this clinical trial is to compare 2 different timepoints for clamping the umbilical cord at birth for term-born infants with a prenatal diagnosis of congenital heart disease (CHD). The main questions it aims to answer are: Does Delayed Cord Clamping at 120 seconds (DCC-120) or Delayed Cord …

37 - 42 years of age All Phase N/A
L Leah Gramlich, MD

Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients

Malnutrition is common in surgical patients. Many studies have shown a clear association between malnutrition and poor surgical outcomes. Parenteral nutrition (PN) is a nutrition intervention that is given by vein and can be safely provided to malnourished patients. It contains carbohydrates, fats, and protein just like you would normally …

18 years of age All Phase N/A
A Ailar Ramadi, PhD

Effectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty Prostheses

The purpose of the study is to determine if knee replacement performed using Journey II implant is different from two other standard-of-care knee replacements using Stryker and Zimmer in terms of knee movements and forces, walking patterns, pain, and function after surgery.

50 - 75 years of age All Phase N/A
E Erin Kelly, MD FRCSC

Antibiotic Prophylaxis for Bladder Botox

Injection of Botox into the bladder is a common treatment for overactive bladder. Postoperative bladder infection is one of the more frequently reported complications of this procedure. Prophylactic antibiotics given at the time of bladder Botox for the reduction of postoperative bladder infection have not been well studied. The main …

18 years of age Female Phase 4

Immune-Mediated Pathophysiology And Clinical Triage Program

Many people develop joint pain, stiffness and swelling due to their cancer treatment that targets the immune system. The severity of symptoms ranges from mild to debilitating and sometimes requires delaying or stopping cancer treatment. The usual plan is to discontinue cancer treatment and give relatively high doses of a …

18 years of age All Phase 2

Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment

The purpose of this observational study is to evaluate the utility of the S100A7 immunohistochemistry signature-based assessment - STRATICYTE - in determining the risk of progression to cancer of clinically suspicious oral lesions.

15 - 90 years of age All Phase N/A
E Eric C Parent, PhD

The Adult Degenerative Scoliosis Exercise Trial (Pilot Study)

Adult degenerative scoliosis is the most common spine deformity in adults. Patients present a lateral curvature of the spine and vertebra rotation. Curves meeting indications for treatment affect 24% of the aging adult population. Adult scoliosis causes pain, curve progression, and cosmetic deformity affecting quality of life and function. Pain …

50 years of age All Phase N/A
M Matt Hicks, MD, PhD

The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program

Neonatal Abstinence Syndrome (NAS), is a common and costly problem in Alberta that affects approximately 250 babies per year exposed to drugs during pregnancy. Unfortunately, this has become more common in the last 10 years. Babies with NAS can be very difficult to care for with poor feeding, diarrhea, and …

years of age Female Phase N/A
M Margie Davenport, PhD

Sleep Disordered Breathing, Endothelial Function, and Adverse Events in Pregnancy

This is a prospective longitudinal cohort study whereby pregnant individuals are asked to complete an 8-day testing protocol to measure their sleep and cardiovascular health at two timepoints during pregnancy.

18 years of age Female Phase N/A

Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL)

Autologous, unselected CD3+ lymphocytes collected from apheresis, transfected with a lentiviral vector containing a 2nd generation chimeric antigen receptor (CAR) consisting of a scFv recognizing CD19 and dual co-stimulatory intracellular signaling domains (4-1BB and CD3ζ).

2 - 70 years of age All Phase 1/2

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