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Edmonton, Canada Clinical Trials

A listing of Edmonton, Canada clinical trials actively recruiting patients volunteers.

Found 278 clinical trials

Middle Cerebral Artery Aneurysm Trial

Intracranial aneurysms located on the middle cerebral artery (MCA) are considered by many surgeons to represent a distinct subgroup of aneurysms for which clipping may still be the best management option. Most MCA aneurysms are accessible, proximal control can readily be secured in case of rupture, and clip application can …

18 years of age All Phase N/A
M Melanie Chouinard

Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment

Dental cavities are among the most frequent diseases that affect teeth, particularly in patients who are treated with braces due to the difficulty in maintaining good oral hygiene in the presence of the mouth appliances. The white spot lesion (WSL) is the first clinical sign of cavities that presents itself …

12 - 21 years of age All Phase N/A
J Jaynie Yang

Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?

This proof-of-principle study will determine if breathing an increased concentration of oxygen above the concentration in normal room air results in changes in the sensory and motor function in people with subacute or chronic, severe spinal cord injury (SCI).

18 - 65 years of age All Phase N/A
S Shayna Zelcer, MD

Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

The efficacy of treatment with metformin for promoting cognitive recovery and brain growth in children/adolescents treated for medulloblastoma will be investigated in a multi-site Phase III randomized double-blind placebo-controlled parallel arm superiority trial. Specifically, in children/adolescents aged 7 years to 17 years and 11 months who have completed treatment for …

7 - 17 years of age All Phase 3

Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)

This is a post-trial access (PTA) open-label, single-arm study in Multiple Myeloma participants who continue to derive clinical benefit from elranatamab monotherapy in the Pfizer-sponsored elranatamab Parent Studies.

18 years of age All Phase 4
M Mithun Rajshekar, PhD

Conditioning Electrical Stimulation to Improve Outcomes in Cubital Tunnel Syndrome

Cubital tunnel syndrome is the second most common compression neuropathy. In severe cases, functional recovery, even with surgery, is often poor. Therefore, alternative adjunct treatments capable of increasing the speed of nerve regeneration are much needed.

18 - 79 years of age All Phase N/A
J Jane E Yardley, PhD

Exercise and the Menstrual Cycle in Type 1 Diabetes

Female participants with type 1 diabetes using oral contraceptives will be asked to wear a continuous glucose monitor for at least three days on two separate occasions (once during the last week of active pills and once during the no pill/placebo pill phase of the menstrual cycle). An exercise session …

18 - 50 years of age Female Phase N/A

Tamoxifen Versus Etoposide After First Recurrence in GBM Patients

The investigator propose a single-center randomized phase II controlled study designed to compare the management of first recurrence of GBM using etoposide versus tamoxifen.

18 - 65 years of age All Phase 2
E Eric C Parent, PhD

The Adult Degenerative Scoliosis Exercise Trial (Pilot Study)

Adult degenerative scoliosis is the most common spine deformity in adults. Patients present a lateral curvature of the spine and vertebra rotation. Curves meeting indications for treatment affect 24% of the aging adult population. Adult scoliosis causes pain, curve progression, and cosmetic deformity affecting quality of life and function. Pain …

50 years of age All Phase N/A
G Georg SCHMOLZER

Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation

When a baby is born with a low heart rate or no heart rate, the clinical team must provide breathing support and chest compressions (what is call cardiopulmonary resuscitation or CPR). In some situations, the clinical team also need to give medications to help the heart rate increase. During CPR, …

- 20 years of age All Phase 1

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