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San Paulo, Brazil Clinical Trials

A listing of San Paulo, Brazil clinical trials actively recruiting patients volunteers.

Found 327 clinical trials
N Nelson Hamerschlak, MD, PhD

Expansion of Virus-Specific Lymphocytes for Cell Therapy

Infections and reactivation of human cytomegalovirus (CMV), adenovirus, Epstein-barr and polyoma virus infections are frequent causes of morbidity and mortality and are a source of serious complications in patients undergoing allogeneic bone marrow transplantation. In this project we will prepare specific T lymphocytes from blood donor, select cells CMV-specific by …

18 - 75 years of age All Phase 1
M Marcelle Goldner Cesca, MD

Wearable Enhanced Fitness Tracking for Metastatic Breast Cancer Patients Using Endocrine Treatment and Palbociclib

Combining a fitness tracker technology with real-time patient-reported outcome monitoring associated with interventions through a health care app is a novel strategy to evaluate metastatic breast cancer patients using Palbociclib and endocrine treatment.

18 years of age Female Phase N/A

Evaluation of Sequencing of Anthracyclines and Taxanes for Locally Advanced HER2-negative Breast Cancer

Phase III randomized clinical trial evaluating the sequencing of anthracyclines and taxanes in neoadjuvant therapy for locally advanced HER2-negative breast cancer.

18 years of age Female Phase 3
C Celso RF Carvalho, PhD

Impact of Remote Vital Signs Monitoring in People Using Long-term Oxygen Therapy

Assess quality of life of patients using prolonged oxygen therapy

18 - 85 years of age All Phase N/A

The Solaris DE Endoprosthesis for the Treatment of AV Access Stenosis or Occlusion

The goal of this clinical trial is to demonstrate the safety and efficacy of Solaris DE Endoprosthesis in the treatment of stenosis or occlusion within the outflow circuit of the dialysis access including arteriovenous (AV) fistula and synthetic AV graft. Participants will be treated with Solaris DE Endoprosthesis. Researchers will …

18 years of age All Phase N/A
M Marcia Volpe, Doctor

Positive Pressure Therapy to Optimize LUNG Function After Heart Surgery

The most common cardiac surgeries are myocardial revascularization and valve replacement or plastic surgery. In the postoperative period of cardiac surgeries, the incidence of pulmonary complications ranges from 30% to 50% and is associated with increased length of hospital stay and morbidity and mortality. To reduce or minimize the occurrence …

18 years of age All Phase N/A
M Matheus Liguori Feliciano da Silva D Silva, MD

Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU

Renal dysfunction is a frequent complication in patients admitted to intensive care units (ICUs), associated with high morbidity and mortality. Current therapeutic options to prevent this condition are limited and lack robust scientific evidence. This pilot study consists of a multicenter, blinded, randomized clinical trial, unprecedented in the literature to …

18 years of age All Phase 2
P Patrícia Paiva

Valvular Assessment of New Generation Aortic Replacement Devices

The VANGUARD study is an open-label, prospective, randomized trial comparing the long-term outcomes of two advanced bioprosthetic aortic valves, Dafodil® and INSPIRIS Resilia®, in patients undergoing aortic valve replacement (AVR). This study aims to provide robust data on valve durability, safety, and hemodynamic performance, particularly in younger patients who may …

18 - 65 years of age All Phase N/A
A Alfredo E Hoyos, MD

Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction

The goal of this clinical trial is to evaluate if CO2 Lift reduces bruising and pain after Liposuction. The study also aims to explore changes in patient satisfaction. The main questions this study seeks to answer are: Does CO2 lift reduce the extent of bruising at 7 days post-surgery? How …

18 - 65 years of age All Phase 4
A Amanda Vieira

Effect of Aromatherapy for Facial Aesthetics in Alleviating Signs of Aging: Pilot Study

Introduction: aesthetics is one of the specialties for professional nurses and presents a dialogue with Aromatherapy, a practice that uses essential oils (EO) from aromatic plants, being one of the most used integrative therapies for beauty care, youth and well-being. EOs are volatile compounds extracted from the most diverse parts …

45 - 55 years of age Female Phase N/A

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