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A, Concord N Clinical Trials

A listing of A, Concord N clinical trials actively recruiting patients volunteers.

Found 10,489 clinical trials
M Molly K Courish, MSc, PhD(s)

The Role of EDHFs on Blood Pressure Following a Bout of Prolonged Sitting

Canadians spend most of their day in sedentary postures (i.e., sitting, lying, reclining). While the beneficial impacts of physical activity on the heart are well-established, less is known about the consequences during time spent in sedentary postures. Currently, we know that spending time in a bout of uninterrupted sitting disrupts …

18 - 65 years of age All Phase N/A
B Bin Cao

A Trial of HRS-8427 in the Treatment of Adults With Bacterial Pneumonia

The purpose of this study is to evaluate the efficacy and safety of HRS -8427 in patients with HABP/VABP.

18 years of age All Phase 2
J Jie Wang, Professor

A Trial of SHR-A2102 With Other Antitumor Therapies in Advanced Solid Tumors

The study is being conducted to evaluate the safety, tolerability and efficacy of SHR-A2102 with other antitumor therapies in advanced solid tumors to explore the reasonable dosage, safety and efficacy of SHR-A2102 for advanced solid tumors.

18 - 70 years of age All Phase 2

Optimal Bowel Preparation in Geriatric Patients With a Instructional Animation Video Before Colonoscopy

Our study presents an innovative educational approach combining visual and auditory elements, targeting the specific needs of the geriatric population. Generally, before colonoscopy, participants are given a written instruction describing the standard bowel preparation with the use of laxatives and enemas. In our study, in addition to this written instruction, …

60 years of age All Phase N/A
R Rory McCoy

A PIVOTAL STUDY EVALUATING SAFETY and EFFICACY of the SHIRATRONICS MIGRAINE THERAPY SYSTEM

Prospective, multi-center, double blind, randomized, sham-controlled study to evaluate neuromodulation in patient with chronic migraine. The study hypothesis to be tested is the mean reduction in mean monthly headache days between patients in treatment versus sham.

22 years of age All Phase N/A
S Samwel Chirchir, RN, BS

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

The purpose of this study is to compare a 6-month regimen of high-dose rifampicin (RIF), high-dose isoniazid (INH), linezolid (LZD), and pyrazinamide (PZA) versus the World Health Organization (WHO) standard of care (SOC) treatment for tuberculosis meningitis (TBM).

15 years of age All Phase 2

A Study to Evaluate the Effect of Food on the Single-Dose Pharmacokinetics and a Drug-Drug Interaction Evaluation of Itraconazole and Rifampin on INCB123667 When Administered Orally to Healthy Adult Participants

This study will be conducted to evaluate the effect of food on the single-dose pharmacokinetics and a drug-drug interaction evaluation of itraconazole and rifampin on INCB123667 when administered orally to healthy adult participants.

19 - 55 years of age All Phase 1
X Xiao Yang

A Study Comparing the Necessity of a Second Transurethral Resection in High-Risk Non-Muscle-Invasive Bladder Cancer Patients With Negative Results From Post-Initial Resection Urine Genome-Wide Low-Depth Sequencing

This study is a prospective, randomized, multicenter clinical trial aiming to enroll 428 patients with non-muscle-invasive bladder cancer (NMIBC) from the Department of Urology at Jiangsu Provincial People's Hospital and its affiliated centers, who have undergone their initial transurethral resection and are scheduled for a second resection. Within 1-6 weeks …

18 - 80 years of age All Phase N/A
J Joe Wallace

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

This is a first-in-human (FIH), Phase 1/2a, multi center, open-label, single treatment, dose escalation and expansion study designed to determine the safety and tolerability of STM-416 in patients with bladder cancer.

18 years of age All Phase 1/2
B Brian Green, PhD

A Proprioceptive Training Program Using an Uneven Terrain Treadmill for Patients With Ankle Instability

The ROCKY REHAB trial will provide a pragmatic approach to evaluate if incorporating a rocky, uneven terrain treadmill into the proprioceptive rehabilitation received during physical therapy can improve outcomes and reduce reinjury rates in patients with ankle instability.

18 - 49 years of age All Phase N/A

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