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A, Concord N Clinical Trials

A listing of A, Concord N clinical trials actively recruiting patients volunteers.

Found 10,489 clinical trials

A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01

The goal of this clinical trial is to evaluate the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of VX-01 as stand-alone treatment for Diabetic Retinopathy of Non-Proliferative Type (NPDR). The primary objective of the study is to evaluate the efficacy of daily oral doses of VX-01 versus placebo following 52 …

18 years of age All Phase 2
S Sandra Buchanan

Evaluating a Digital Single-session Intervention for Adolescent Mental Health in New Zealand

Currently, one in five rangatahi (young people) in Aotearoa report difficulty accessing support for their mental health concerns. This treatment gap has prompted academics and clinicians to consider whether online and/or school-based interventions can increase access to evidence-based mental health care. This research is a randomised controlled trial to evaluate …

12 - 14 years of age All Phase N/A

Pharmacokinetics of GH001 Delivered Via a Proprietary Aerosol Delivery Device in Healthy Subjects

The primary objectives of this trial are to determine the pharmacokinetic (PK) profile and the safety and tolerability of GH001 delivered via a proprietary aerosol delivery device in healthy subjects after single-dose administration and a single-day individualized dosing regimen (IDR). As secondary objectives, the mebufotenin PK/ pharmacodynamic (PD) relationship, the …

18 - 64 years of age All Phase 1
G Guillermo M Wippold, PhD

Evaluating the Fade to Fitness Program: A Barbershop-based Program for Black Men

The Fade to Fitness Program is a targeted intervention designed to improve the holistic health and quality of life among Black men. This comprehensive initiative focuses on four key health behaviors: Physical Activity, Healthy Eating, Stress Management, and Depression Management. It is grounded in psychological and social theories like Self-Determination …

18 - 90 years of age Male Phase N/A
H Hong Zhao, doctor

A Study of MRG006A in the Treatment of Patients With Advanced Solid Tumors

The objective of this study is to assess the safety, efficacy, pharmacokinetics, and immunogenicity of MRG006A in patients with advanced solid tumors.

17 - 85 years of age All Phase 1/2
S Senior Project Manager Senior Project Manager

A Study to Evaluate the Effect of Fish Oil Concentrate on Skin Function

The primary objective of the study is to determine the benefits of the food product EPAX Omega 3-9-11 on skin function. Benefits (if any) will be determined by evaluating biophysical measurements of the face and inner forearm. Moreover, the study will determine the dosage effect of Omega-3-9-11 on these measurements.

35 - 65 years of age All Phase N/A
C Christina Teng

A Study of AK146D1 for Injection in the Treatment of Advanced Solid Tumors

This is an first-in-human, Phase I clinical study aimed at evaluating the safety, tolerability, PK, immunogenicity, and preliminary antitumor efficacy of AK146D1 for injection in advanced solid tumors.

18 - 75 years of age All Phase 1

A 3- to 5-day Clinical Trial of Levamisole in Loiasis Infected Subjects

The aim of the study is to evaluate the safety and efficacy of a 3- and 5-day course of levamisole (2.5 mg/kg) in management of loiasis microfilaremia.

18 - 65 years of age All Phase 2/3
O Olivia Roath

A Frequency-Modulated Music Intervention to Enhance Cognitive Processing Therapy (CPT) for PTSD

The goal of this clinical trial is to learn if the addition of frequency filtered music (Safe and Sound Protocol) to daily cognitive processing therapy improves effectiveness for reducing PTSD symptoms. The main questions it aims to answer are: Does the addition of frequency filtered music reduce PTSD symptoms for …

18 years of age All Phase N/A
B Berge Minassian, MD

A Safety and Efficacy of Intrathecally Administered ION283 in Patients With Lafora Disease

This study will test the safety and efficacy of multiple doses of ION283 administered as intrathecal (IT) injections by lumbar puncture (LP). All subjects will receive ION283. The dose level of 15 mg will be studied in all subjects.

10 - 18 years of age All Phase 1/2

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