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A, Concord N Clinical Trials

A listing of A, Concord N clinical trials actively recruiting patients volunteers.

Found 10,489 clinical trials
D Dayanne Antonio, PhD student

Evaluating a Mat-Based Biometric Vibration System for Sleep and Daily Recovery

The goal of this randomized clinical trial is to learn whether a low-frequency "kinetic wellness" mat (a comfortable mat that gently vibrates) can improve stress recovery, sleep quality, mood, and attention in healthy adults ages 18-45. The main questions it aims to answer are: After 3 weeks, does regular use …

18 - 45 years of age All Phase N/A
F Flory Nkoy, MD, MS, MPH

A Novel mHealth Intervention to Improve Outcomes of Children With Medical Complexity

Children with medical complexity (CMC) are the most vulnerable of children with chronic diseases, who have complex, multisystem chronic diseases affecting ≥3 organ systems, severe functional limitations and technology dependencies. CMC have high health care needs, and account for 40% of hospitalized children and 35% of all pediatric health care …

1 - 18 years of age All Phase N/A
S SEGRETERIA SCIENTIFICA

Clinical Investigation on a Polynucleotide-based Device Used to Improve Skin Hydration

Adequate skin hydration is critical for maintaining healthy skin. Moreover, dehydration, together with reduction in cell renewal, loss of radiance, elasticity and firmness, is involved in skin aging. Injectable anti-aging products have been widely used for aesthetic improvement of the skin. In recent years, new filler products made from High …

18 - 70 years of age All Phase N/A

Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Anxiety in Adolescents

Trial title: A Randomized, Double-blind Sham-controlled Clinical Trial to Evaluate The Efficacy of Electrical Vestibular Stimulation (VeNS), Compared to a Sham Control For The Management Of Anxiety in Adolescents - The Modius Calm Adolescent Study The aim of this study: This investigation aims to evaluate the effects of VeNS for …

12 - 17 years of age All Phase N/A
W Wenzhao Guan

Schneider Membrane Preservation With In Situ Osteogenesis: A Modified Maxillary Resection Study

This case series study aimed to find out if a new surgical technique that preserves the sinus membrane during upper jaw removal can help patients regenerate bone and recover function better after surgery. The study included two female patients with jaw tumors who were not suitable for or did not …

18 - 75 years of age All Phase N/A
C Caitlin Hall, PhD

CALM Study: Can A Prebiotic Fibre bLend Improve Stress, Mood, and Anxiety?

This clinical trial will investigate whether a powdered prebiotic fibre blend can improve perceived stress levels in healthy adults with mild-moderate stress levels.

18 - 50 years of age All Phase N/A
H Herui Yao

A Study of BRY812 for Injection Alone in Subjects With Advanced Malignancies

This is a Phase I, multicenter, open-label, single-arm and first-in-human clinical study of BRY812 for injection. The study objectives are to evaluate the safety, tolerability, pharmacokinetic profile, anti-tumor activity and immunogenicity of BRY812 for injection in patients with advanced malignancies. Patients will receive treatment every 3 weeks until intolerable toxicity, …

18 years of age All Phase 1
P Philippe Nadeau, Ph.D.

Immunoglobulins in Multiple Myeloma Patients Receiving a BCMA-Directed T Cell Engager

Bispecific antibody therapies targeting BCMA (B-cell maturation antigen) represent a novel therapeutic approach for patients with multiple myeloma. They are currently used in cases of refractory multiple myeloma but are also being investigated in earlier lines of treatment. However, these new therapies can lead to deeper immunosuppression and exacerbate an …

18 years of age All Phase 4
C Changsong Qi, MD

A Phase I Study of NK042 Cell Injection in Advanced Solid Tumors

This is a single-arm, open-label, multi-center phase 1 clinical study designed to evaluate the safety and preliminary efficacy of NK042 cell injection in patients with advanced solid tumors.

18 - 70 years of age All Phase 1
H Henrik Schytz, MD

Safety and Efficacy of Botulinum Toxin A in Patients With Posttraumatic Headache

The study is an investigator-initiated randomized, placebo-controlled, double-blind, parallelgroup trial. Eighty subjects with PTH will be included and randomized 1:1 for treatment with BTX-A or placebo (isotonic saline). The study comprises a 4-week baseline phase before injection of either active drug or placebo followed by a 12-week evaluation period. Treatment …

18 - 80 years of age All Phase 3

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