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A, Concord N Clinical Trials

A listing of A, Concord N clinical trials actively recruiting patients volunteers.

Found 10,489 clinical trials
M Monica Smersh

Effectiveness of Frontal Plane Adaptability in a Novel Foot Prosthesis

People with lower extremity amputation (LEA) have persistent problems with balance, falls, residual limb pain, functional mobility, cognitive attention during gait, and satisfaction with participation in daily activities, despite using prostheses. The purpose of this randomized clinical trial is to advance understanding of how dynamic foot design features may help …

16 years of age All Phase N/A
J Junyu Wu, ph.D

A Study of KC1036 in Patients With Advanced Solid Tumors

The purpose of this study is to evaluate the safety,tolerability, pharmacokinetics, and preliminary efficacy of KC1036 in participants with advanced recurrent or metastatic solid tumors. The trial will be divided into three parts: dose-escalation phase, dose-expansion phase, RP2D-extension phase.

18 years of age All Phase 1

A Study of DB-1311 in Advanced/Metastatic Solid Tumors

This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1311 in subjects with advanced solid tumors.

18 years of age All Phase 1/2
Y Yael Apter Levy, Phd

A Brief Emotion Focused Therapy for Preschoolers With Anxiety Disorders

The study will comprise of three groups of children (n=40): 1. A group receiving a novel short-term dynamic play therapy. 2. Dyadic therapy 3. Control group who will not receive therapy. All children will be assessed for psychopathology (anxiety, depression and behavioral problems) using standardized instruments such as semi-structured interview …

3 - 6 years of age All Phase N/A
M Maria I Grigos, PhD

A Randomized Control Trial of Motor-based Intervention for CAS

Childhood apraxia of speech (CAS) is a complex, multivariate speech motor disorder characterized by difficulty planning and programming movements of the speech articulators (ASHA, 2007; Ayres, 1985; Campbell et al., 2007; Davis et al., 1998; Forrest, 2003; Shriberg et al., 1997). Despite the profound impact that CAS can have on …

29 - 95 years of age All Phase N/A
J Jury Candelario, LCSW

Testing a Self-management Intervention in HIV+ Asian Pacific Americans

HIV infection rates are on a rapid rise within Asian Pacific Americans (APA) communities, with 80% of new infects being men. The purpose of this study is to adapt and evaluate the feasibility of a 4-session, 4-week family-informed self-management intervention protocol to promote health among APA men with HIV (APAMHIV). …

18 - 99 years of age All Phase N/A
A Amanda Adler, BA

Fecal Microbiota Transplantation as a Strategy to Eradicate Resistant Organisms

This protocol will evaluate fecal microbiota transplantation (FMT) as a strategy to eradicate intestinal colonization of extended-spectrum resistant (ESC-R) Enterobacteriaceae in pediatric patients. FMT will be performed on subjects with a history of at least one infection due to ESC-R Enterobacteriaceae. This protocol aims to determine the feasibility, safety, tolerability, …

7 - 21 years of age All Phase 1
Y Yi Ba, Professor

A Study of SKB315 in Patients With Advanced Solid Tumors

This is a multicenter, open-label, multiple-dose dose finding and expansion study to evaluate the safety, tolerability, pharmacokinetic(PK) profile, and anti-tumor efficacy of SKB315 for injection in patients with advanced solid tumors.

18 - 80 years of age All Phase 1
M Mireille Joussemet, Ph.D.

Improving Preschoolers' Mental Health: A RCT Assessing Two Parenting Programs

The goal of this randomized control trial (RCT) is to assess the superiority of the How-to Parenting Program in improving autonomy support and preschoolers' mental health (i.e., decreases externalizing problems) among vulnerable families. The main question it aims to answer is: Can teaching concrete parenting skills that target empirically-based parenting …

18 years of age All Phase N/A
R Rieneke Terink, Dr

Effect of Collagen/Vitamin C in Jumper's Knee; a RCT

Patellar tendinopathy (PT) is a tendon overuse injury with high prevalence rates in elite and recreational athletes. PT sometimes results in a prolonged absence from sport participation, hampering individuals to achieve their desired performance levels and to benefit from the health related effects of sports participation. Many treatment options are …

16 - 40 years of age All Phase N/A

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