Advanced Filters
noise

Mild Cognitive Impairment Clinical Trials

A listing of Mild Cognitive Impairment medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 681 clinical trials
S Sharmila SAGNIER, Dr

Training Cognition With Neurofeedback After Stroke

Post-stroke cognitive impairment (PSCI) is a common source of invisible disability. The actual techniques of cognitive remediation have been reported to have only a small effect, justifying the need to foster research in this field. Real-time functional MRI neurofeedack (rt-fMRI NF) is a procedure of brain-machine interface supporting self-regulation of …

18 - 75 years of age All Phase N/A
B Barbara Ukropcova, Prof.

Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention

Due to the increasing incidence of dementia and the lack of causal treatment, non-pharmacological interventions represent an attractive and effective therapeutic strategy of neurodegenerative diseases, such as Alzheimer's disease. The aim of the study is to assess the impact of a supervised 9-month intervention with aerobic-strength training and nutritional counseling …

60 - 80 years of age All Phase N/A
M Martino Belvederi Murri, MD

Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS

Despite its significant impact on individuals and healthcare systems, substantial gaps remain in the clinical and rehabilitative management of depression in oncology patients. Depression in cancer patients is often under-recognized and untreated, and screening tools and structured healthcare pathways are lacking. Even when depression is identified in oncology patients, evidence …

18 - 100 years of age All Phase N/A
J Jinping Shi, Bachelor

A Sitting Tai Chi Programme for Chronic Stroke Survivors With Post-stroke Cognitive Impairment

Introduction Stroke remains the third leading cause of death and disability combined. Post-stroke cognitive impairment (PSCI) is a common neurological sequela that may affect up to 80% of stroke survivors. Several systematic reviews and studies indicated that Tai Chi benefits patients with mild cognitive impairment, leading to significant improvement in …

18 years of age All Phase N/A
I Imran Amjad, Phd

Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors.

This study aims to: Compare tele-rehabilitation and conventional rehabilitation for cognitive improvement after stroke. Evaluate changes in cognitive function using standardized assessment tools. Determine whether tele-rehabilitation is as effective as conventional therapy. Improve evidence-based rehabilitation strategies for stroke survivors.

50 - 80 years of age All Phase N/A
J João Ferreira-Coimbra, MD

Virtual Reality for Recovery After Intensive Care (PICS)

The goal of this clinical trial is to learn if virtual reality (VR) helps improve thinking and memory skills in adults who have stayed in the intensive care unit (ICU). The study focuses on people who needed a breathing machine or stayed in the ICU for several days and are …

18 years of age All Phase N/A

Innate Immunity Stimulation Via TLR9 in Early AD

This single-center, double-blind, placebo-controlled study will recruit in total 39 participants with either Mild Cognitive Impairment due to Alzheimer's disease (MCI) or Mild Alzheimer's disease dementia (mild AD). There will be 3 Dose levels. An initial cohort of 13 subjects will be randomized to a Dose level 1 (0.1 mg/kg …

60 - 85 years of age All Phase 1
B Brenna R Renn, PhD

Engage for Late-Life Depression and Comorbid Executive Dysfunction

Although there are an increasing number of mental health treatment adaptations for older adults, there are still a number of factors to consider when making these adaptations. Cognitive decline is one such factor that places significant burden on older adults and can interfere with traditional mental health therapies. Engage is …

60 years of age All Phase N/A
T Tineke Van Vrekhem

Spatial Navigation for the Early Detection of Alzheimer's Disease.

Alzheimer's Disease (AD) is the most common form of dementia and may contribute to 60-70 % of all cases. An early, accurate diagnosis of AD will become increasingly important with disease-modifying therapies. Different types of fluid and neuroimaging biomarkers are available for the early detection of AD. However, implementation of …

50 - 80 years of age All Phase N/A
J Jared Benge, PhD

Paper-Based and Smartphone-Based Memory Supports

Alzheimer's disease and related dementias lead to marked declines in daily functioning, independence, and quality of life. One of the earliest cognitive changes in these conditions is impairment in prospective memory, or the ability to remember future intentions such as taking medications at a given time. Prior intervention studies that …

50 years of age All Phase N/A

Simplify language using AI