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Mild Cognitive Impairment Clinical Trials

A listing of Mild Cognitive Impairment medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 681 clinical trials
R Raymond Jones, Ph.D.

High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV

This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition. The overall goals of this proposal are to determine whether 16 weeks of structured high-intensity interval training (HIIT) can overcome vascular and cognitive impairments (Aim 1) to …

50 years of age All Phase N/A
S Sudeep Aditham

Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease

The goal of this clinical trial is to evaluate the safety and tolerability of a novel deep brain stimulation (DBS) of the Subthalamic Nucleus (STN) and Nucleus Basalis of Meynert (NBM) to treat cognitive and cognitive-motor symptoms in individuals with Parkinson's disease. The main question it aims to answer is: …

21 - 80 years of age All Phase N/A
F Francesco Corallo

Dementia and Mild Cognitive Impairment: Assessment of Cognitive Functioning, Functional Autonomy, and Neuropsychiatric Symptoms.

Dementia, in its various forms, is characterized by a generalized cognitive decline that can significantly compromise personal autonomy and quality of life. Mild Cognitive Impairment (MCI), although not classified as an overt form of dementia, represents a condition at evolutionary risk and is considered a crucial transitional stage for the …

50 - 86 years of age All Phase N/A
K Ka Hei Christy Tang, Degree

Cognitive Stimulation Therapy Group for Residential Home Residents With Dementia and Mild Cognitive Impairment

The research aims to investigate the effectiveness a cognitive stimulation therapy group for older adults with dementia and mild cognitive impairment living in residential homes. This study adopts a multicenter randomized control trial two arms research design. The randomized controlled trial will compare a typical 14-session cognitive stimulation therapy group …

60 years of age All Phase N/A
G George Kuchel, MD

The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults

The goal of this clinical trial is to test the effects of MitoQ supplementation in older adults and frail older adults with physical dysfunction and/or cognitive dysfunction. The main question\[s\] it aims to answer are: To compare vascular function, oxidative stress levels, and physical and cognitive function among older adults …

65 - 80 years of age All Phase 2
C Clara Berridge

The "Let's Talk Tech" Tool to Support Decision Making About Technology Use

The goal of this research is to educate people about different technologies to support care at home when someone is experiencing memory difficulties. "Let's Talk Tech" is a new tool to educate people about technologies commonly used to support care and monitor safety, and help families talk about their feelings …

18 years of age All Phase N/A
S Susan Racette, Ph.D.

Time Restricted Eating in Alzheimer's Disease

This pilot and feasibility study will enable the research team to determine the feasibility of implementing a time-restricted eating regimen among adults with mild cognitive impairment (MCI) and the impact of time-restricted eating on cognitive performance and biomarkers of metabolic health in this population. Study staff will execute the specific …

55 - 89 years of age All Phase N/A
V Valeria Blasi, MD

Validation of a Digital Intervention to Rehabilitate Cognitive Resources

The goal of this clinical trial is to learn if the use of a digital cognitive rehabilitation system named RICORDO, that is flexible and capable of adapting the rehabilitation pathway according to the needs and capacity of the patients will prove effective for subjects with Subjective Memory Complaint or with …

65 years of age All Phase N/A
M Monika Pupíková

Non-invasive Stimulation of Deep Brain Structures to Modulate Working Memory

A study investigating the effects of non-invasive electrical stimulation of deep brain structures on working memory, attention, and executive functions involved in everyday activities. Currently, there is no effective treatment for impairments in these functions. The study will evaluate the effects of non-invasive electrical stimulation in both healthy older adults …

60 - 80 years of age All Phase N/A
Y Yuhan Geng

Binaural Beats for Cognitive Function in Older Adults With Mild Cognitive Impairment in Nursing Homes

This study will evaluate whether binaural beats can improve cognitive function in older adults with mild cognitive impairment living in nursing homes. Participants will listen to 10-Hz alpha-frequency binaural beats through headphones once daily for 30 minutes for 14 consecutive days. Cognitive function, sleep quality, anxiety, and depressive symptoms will …

60 years of age All Phase N/A

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