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Hepatic Porphyria Clinical Trials

A listing of Hepatic Porphyria medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,522 clinical trials
K Katrina Tobin

European Blood Pressure Intensive Control After Stroke

Stroke is the third most common cause of death worldwide and the leading cause of disability. High blood pressure is an important risk factor for stroke. Lowering a person's blood pressure reduces the risk of future stroke or heart attack, and current guidelines recommend treatment to a target of <130mmHg …

40 years of age All Phase 2
Y Yea-Ru Yang, PhD

High Intensity Interval Training in Chronic Stroke

Both gait and cardiovascular dysfunction are primary factors limiting community ambulation for stroke individuals. Increased gait variability and asymmetry contributes to a higher risk of falls, leading to reduced physical activity, decreased cardiorespiratory endurance, and increased walking economy and sympathetic nervous system activity, thereby potentially triggering secondary strokes. Previous studies …

18 - 69 years of age All Phase N/A
J Jeffery Rankin, PhD

AFO Prescription to Optimize Post-Stroke Function

The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis (AFO) treatment options targeting the rehabilitation of individuals post-stroke. To achieve this goal, the investigators will: Identify …

18 years of age All Phase N/A
M Matija Zupan, MD, PhD

Cerebrolysin in Early Stroke Rehabilitation - Tertiary Study

The study evaluates the effect and safety of Cerebrolysin administered during early rehabilitation in patients with moderate neurological impairment after acute ischemic stroke, conducted at the Department of Vascular Neurology and Intensive Neurological Therapy, UMC Ljubljana.

18 years of age All Phase N/A
B Beverly Allen, BS

Utility of CC7 Transfer in Stroke Subtypes

The purpose of this study is to evaluate the limb functional improvement after contralateral C7 root transfer in stroke patients.

18 - 65 years of age All Phase N/A
W Wolf-Rüdiger Schäbitz, MD

SmartWatch-driven AF Detection in Stroke Patients

Unrecognized atrial fibrillation (AF) is a common cause of ischemic stroke. Implantable event monitors (ICM) are the gold standard for continuous heart rhythm monitoring but they have been implemented in very few patients after stroke due to high invasiveness and high costs. In this trial, patients with implanted ICMs (Medtronic …

60 years of age All Phase N/A
G Guangxiong Yuan

Endovascular Treatment for eXtra-Large Ischemic Stroke

The role of endovascular thrombectomy in patients with extra-large ischemic burden is still unclear. The XL STROKE-2 randomized trial is aiming to investigate the efficacy and safety of mechanical thrombectomy in acute extra-large ischemic stroke patients with large vessel occlusion.

18 years of age All Phase N/A
L Lena Geiger-Primo, MD

Cognitive Recovery After Post Stroke Delirium (RECOVER)

RECOVER is a Proof-of-Concept study on cognitive functioning following a longitudinal design with three measurements (during the acute- and post-acute phases of a stroke and a 3-month follow-up) and two equally-sized stroke patient groups: a post-stroke delirium(PSD), and a non-PSD group (control group). Cognitive functioning will be assessed using a …

60 years of age All Phase N/A
E Evan Burr, BA

Mechanisms of Visual Restoration After Occipital Stroke

This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how …

21 - 80 years of age All Phase N/A
J Jichang Luo

MPR for Stroke Risk Assessment of ICAS

Intracranial atherosclerotic stenosis (ICAS) carries substantial stroke risk despite optimal medical treatment. Current risk stratification relies primarily on stenosis severity, but novel hemodynamic markers may improve prediction. In this multiple prospective registry study we aim to investigate whether regional hemodynamics, measured by a novel Magnetic resonance imaging-derived Pressure Ratio (MPR) …

18 - 80 years of age All Phase N/A

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