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Hepatic Porphyria Clinical Trials

A listing of Hepatic Porphyria medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,478 clinical trials
K Keith E Gordon, PhD

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern …

18 - 80 years of age All Phase N/A

Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-B )

To compare the door-to-puncture time of patients with hyperacute ischemic stroke (between 4.5-6 hours after the onset of symptoms) treated in a standard stroke unit adherent to guidelines versus treated in Emergency Stroke Unit (a new stroke unit based on low-field magnetic resonance imaging).

18 years of age All Phase 2
S Steven Levy, MD

Neurologic Stem Cell Treatment Study

This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. …

18 years of age All Phase N/A
f faculty of physical therapy

Effect of Functional Electrical Stimulation on Hand Functions in Stroke Patients

Background: Hand dysfunction is one of the most disabling consequences of stroke and significantly limits independence in activities of daily living. Recovery of fine hand function remains incomplete in many patients despite conventional rehabilitation. By facilitating muscle activation and promoting neuroplasticity, Functional electrical stimulation (FES) has emerged as a promising …

40 - 60 years of age All Phase N/A
H Hao-Yuan Hsiao

Treadmill Oscillation Walking to Improve Weight Transfer During Gait Following Stroke

This study aims to determine the immediate and short-term effects of treadmill oscillation walking (TOW) exercise on hip and knee neuromechanics and gait characteristics in individuals post-stroke. It was hypothesized that compared to baseline, individuals poststroke (N=15) will show increased hip abductor and knee extensor muscle activity and torque production, …

18 years of age All Phase N/A

Effects of Minocycline on Patients With Ischemic Stroke Undergoing Intravenous Thrombectomy

Minocycline is the second generation of tetracycline. Because of its lipophilicity, it has high penetrance of blood-brain barrier. Animal model studies have shown that minocycline can reduce cerebral damage after ischemic stroke, and its mechanism involves multiple molecular pathways, such as antioxidant, anti-inflammatory, anti apoptotic pathways, and protection of blood-brain …

18 - 85 years of age All Phase 4
T Tanvi Bhatt, PhD

Effect of NMES on Balance and Fall Risk in Chronic Stroke

The aim of this study is to describe the effect of neuromuscular electrical stimulation (NMES) in the form of functional electrical stimulation (FES) applied to different lower limb muscles on reactive balance and gait performance in stroke participants. Methods: Twenty individuals with chronic stroke will be asked to perform an …

18 - 90 years of age All Phase N/A
X Xingyue Hu, Prof.

Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion

This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy evaluation and prognostic prediction of the LVO patients with low NIHSS.

18 years of age All Phase N/A
V Vicky Chan, DPT

Wearable Device and Behavioral Support for Enhancing Arm Use After Stroke

The goal of this study is to determine the effectiveness of behavioral support and feedback from a wearable device that senses arm movement in improving upper extremity function in a pilot, randomized controlled trial with chronic stroke patients

18 - 84 years of age All Phase N/A
B Binash Afzal, PhD

Mobile Applications for Exercise Adherence and Hand Function in Chronic Stroke.

Stroke is a clinically defined syndrome characterized by an acute, focal neurological deficit due to vascular damage in the central nervous system. It is the second leading cause of death and disability globally. Stroke is not a singular disease but results from a variety of risk factors, disease processes, and …

35 - 75 years of age All Phase N/A

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