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Hepatic Porphyria Clinical Trials

A listing of Hepatic Porphyria medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,478 clinical trials
M Matthias Brendel, MD

Inflammatory faCtors AfteR acUte Ischemic Stroke

ICARUS is an interventional single-centre hospital-based cohort study in patients admitted to the stroke unit with an acute ischemic stroke. The aims of the study are to i) define the characteristics and determinants of microglial activation after human stroke, and ii) assess the correlation of microglial activation with circulating inflammatory …

50 years of age All Phase N/A
M Melanie Arnold

Strategy for Improving Stroke Treatment Response

SISTER is a Phase-II, prospective, randomized, placebo-controlled, blinded, dose finding trial that aims to determine the safety and preliminary efficacy of TS23, a monoclonal antibody against the alpha-2 antiplasmin (a2-AP), in acute ischemic stroke.

18 years of age All Phase 2
m mohamed G. Zeinhom, MD

Acetyl-leucine in Post-stroke Ataxia

Along with the current clinical trial, the efficacy and safety of 4 gram of acetyl-leucine daily for three months in patients with post-stroke ataxia following posterior-circulation ischaemic stroke assessed through BBS, SARA, and mRS, and possible adverse effects.

18 - 80 years of age All Phase 3
X Xingzhi Wang, MD

Circulating circRNA in Acute Ischemic Stroke

CRAST is to analyze the expression pattern of circular RNA (circRNA) by bioinformatics analysis in patients with acute ischemic stroke and healthy control. The candidate circRNA will be verified as biomarkers for the detection and prognosis of acute ischemic stroke.

18 years of age All Phase N/A
P Pr Tae-Hee CHO CHO, MD

CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke - HIBISCUS-STROKE II

Ischemic stroke is the first cause of acquired disability of the adult, the second cause of dementia and the third cause of death in the industrialized countries, what constitutes à major public health issue. Stroke is characterized by a cerebral parenchymal lesion due to an ischemic mechanism (85% of the …

18 years of age All Phase N/A
R Ruquan Han, M.D., Ph.D

Oxygen Concentration Target in Stroke Endovascular Treatment

The goal of this clinical trial is to compare the effects of different concentrations of normobaric oxygen on early neurological improvement in acute ischemic stroke (AIS) patients receiving endovascular therapy (EVT). The main questions it aims to answer are: Evaluating the impact of normobaric high-concentration oxygen versus low-concentration oxygen on …

18 years of age All Phase N/A
C Christine Pol, PhD

Virtual Reality Based Rehabilitation After Ischemic Stroke

Use the template below as a guide to write a brief study description in plain language. Tailor the text that appears in brackets and yellow to your research study. To finalize, delete the text in italics. The goal of this single-arm study is to explore the use of early virtual …

18 years of age All Phase N/A
S Souvik Sen, MD, MS, MPH

Pulse Endovascular ReperFUSION for Acute Ischemic Stroke

Prospective, multi-center, single-arm early feasibility study enrolling a minimum of 15 subjects at up to a minimum of 3 active investigational sites in the United States. The subjects must be diagnosed with acute ischemic stroke (AIS), must be post-mechanical thrombectomy, will have had intravenous thrombolytics, and have a visible MCA, …

18 - 85 years of age All Phase N/A
C Claus Z Simonsen, MD

Acute Subcutaneous SemaglutidE in Acute Ischemic sTroke

Can Semaglutide help reduce the damage caused by a stroke? ASSET trial is a national, multicenter, clinical trial, investigating the safety and efficacy of Semaglutide in non-diabetic patients with acute ischemic stroke. Stroke is a worldwide leading cause of long-term disability and death. In the most common type of stroke …

18 years of age All Phase 2
A Andrea Zini, MD

Targeted Temperature Management in Acute Ischemic Stroke

The goal of this interventional trial is to evaluate whether the CB240\_Aurora medical device is effective for targeted temperature management in adult patients with acute ischemic stroke. The main questions it aims to answer are: Is the CB240\_Aurora effective in maintaining normothermia in patients with acute ischemic stroke? Does the …

18 years of age All Phase N/A

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