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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,826 clinical trials
L Liselotte Van Loo, MD

Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease

Infants with congenital heart disease (CHD) are at increased risk for delayed neurodevelopment. Multiple etiological explanations have been proposed, as there seems to be a multifactorial interplay of both prenatal and perioperative factors. The main goal of this research project is to focus on peri-operative physiological risk factors in infants …

- 6 years of age All Phase N/A
E Emmy H Okello

Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda

The goal of this prospective study is to evaluate the feasibility, sustainability, and public health impact of a district-based program for secondary prevention of Rheumatic Heart Disease (RHD) in Uganda.

5 years of age All Phase N/A
L Leilei L Chen

Effect of Individualized Exercise in Elderly Patients With Coronary Heart Disease

The benefits of cardiac rehabilitation have been supported by a large amount of evidence-based medicine. Cardiac rehabilitation can correct cardiovascular risk factors, reduce morbidity and mortality, and improve quality of life.

60 - 75 years of age All Phase N/A
A Anja Lia

Cognitive Behavioural Therapy for Insomnia in Patients With Coronary Heart Disease

Insomnia is prevalent (45%) in CHD patients and associated with significantly increased risk for recurrent cardiovascular events. Insomnia has recently been identified as the third most important risk factor for prognosis. However, very few insomnia patients are identified and receive treatment of insomnia today. CBT-I is the first-line treatment for …

18 - 75 years of age All Phase N/A
L Lydia DeAngelo

Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease

This project aims to validate sex-specific biologic signatures associated with aortic valve disease developed in a large multicenter CMR registry, using unsupervised phenomapping. The aim to use standard and advanced CMR techniques (MRF, DTI, chemical exchange transfer, and radiomics analysis) is to determine advanced CMR predictors of reverse remodeling following …

18 - 90 years of age All Phase N/A
M Michael Khoury, MD

Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease

There are many barriers to heart-healthy lifestyles in pediatric patients with acquired and congenital heart disease. Investigators want to further understand how participants heart and skeletal muscles work together during exercise and evaluate the impact on cardiac function. To do this, the investigators will use magnetic resonance imaging (MRI) to …

10 - 18 years of age All Phase N/A
S Simon James, Dr.

Using Non-Invasive Mapping To Eliminate Structural Heart Disease Ventricular Tachycardia

Ventricular tachycardia (VT) is an abnormal and dangerous heart rhythm affecting the lower chambers of the heart (the ventricles). Patients with structural heart disease caused by previous heart attacks are at an increased risk of developing VT. Current guidelines recommend that patients who develop this abnormal heart rhythm are considered …

18 years of age All Phase N/A
A A/Prof Kumar

Radiotherapy vs Catheter Ablation for Ventricular Tachycardia in Structural Heart Disease

The goal of this randomized clinical trial is to test the efficacy of stereotactic body radiation therapy (SBRT) in treating ventricular tachycardia (VT) in patients with advanced structural heart disease. The main questions it aims to answer are: What is the efficacy of SBRT compared to catheter ablation (CA) in …

18 years of age All Phase N/A
Q Quan Guo

Long-term Remote Ischemic Preconditioning Improves Myocardial Perfusion and Prognosis of Patients After CABG

Remote Ischemic preconditioning (RIPC) has been reported to improve myocardial microcirculation, promote collateral circulation recruitment, and improve myocardial perfusion in patients.Two large randomized controlled trials demonstrated a perioperative cardioprotective effect of RIPC (reduced troponin levels), but did not find that a single preoperative RIPC improved long-term outcomes of coronary artery …

18 - 80 years of age All Phase N/A

PK(Pharmacokinetic) Papyrus Covered Coronary Stent System

The PK Papyrus Covered Coronary Stent System is a coronary stent being used at Methodist Dallas Medical Center for patients with coronary perforations.

years of age All Phase N/A

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