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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,826 clinical trials
P Pugazhendhi Vijayaraman, MD

Angiography and Electrogram Guided Bachmann Bundle Pacing

People eligible for this study are scheduled to have a permanent pacemaker (PPM) or defibrillator device (ICD) implanted as part of their routine care. This device will also have a wire placed in the right atrium (RA) of the heart. As an alternative to the RA, the wire can also …

18 years of age All Phase N/A
J Joseph Klejka, MD

Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)

Heart disease is the leading cause of death for Alaska Native men and the second leading cause of death (after cancer) among women and Alaska Native people overall. The overarching goal of the proposed multilevel, multicomponent intervention, Diet and Active Lifestyle - Yuuyaraq (DAiLY), is to reduce consumption of highly …

18 years of age All Phase N/A
B BUSTIN Aurelien, PHD

Validation of Multi-contrast, High-resolution Cardiac Magnetic Resonance Imaging

Cardiovascular disease (CVD) causes at least 1.8 million European deaths annually, exceeding fatalities from cancer, chronic respiratory disease, and diabetes. Consequently, the fight against CVD has become the main priority of the World Health Organization. In the pursuit of understanding and treating CVD, cardiac magnetic resonance imaging (CMR) has remained …

18 years of age All Phase N/A
M Madeline Cassidy

Lumason® Infusion vs. Bolus Administrations

A phase III study designed as a randomized, within-patient comparison of continuous infusion of diluted Lumason® versus the bolus administration of undiluted Lumason® for degree of LVO and assessment of LV EBD (co-primary endpoints).

18 years of age All Phase 3
A Amrik Khalsa, MD

Pathways to Prevention Food-is-Medicine Trial

The goal of this study is to learn whether combining healthy food access with personalized tools can help families improve heart health and make lasting lifestyle changes. The main questions the study aims to answer are: Do the new tools (PRO-CVH and Triple-C) help families improve their heart health? Which …

6 years of age All Phase N/A
C Christos Mantzios, Cardiology Resident, MD, MSc

Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery

The SHAPE study is a prospective, randomized study evaluating changes in cardiac function in adult patients undergoing cardiac surgery with cardiopulmonary bypass. The study focuses on how cardiac function changes during surgery and whether the depth of anesthesia may influence these changes. Participants are randomly assigned to one of two …

18 years of age All Phase N/A
L Lian Yang

The Clinical Value of Deep Learning-Based Reconstruction Techniques in Cardiac MRI Scanning

By enrolling patients who underwent cardiac MR(Magnetic Resonance) examinations at our center and using randomized allocation, the patients were divided into a study group and a control group. The study group underwent scanning using AI-based(Artificial Intelligence-based) cardiac MRI(Magnetic Resonance Imaging) sequences, while the control group was scanned using non-AI cardiac …

18 years of age All Phase N/A
S Stacey Mazzurco

Sternal Plating High Risk

Participants are being invited to participate in a research study at University Hospitals because they have heart disease and are scheduled for open heart surgery. Currently, UH cardiac surgeons close the sternum (or breastbone) after a sternotomy (procedure that allows a doctor to reach the heart and blood vessels) with …

18 - 89 years of age All Phase N/A
Z Zaid Haddadin, MS

Cardiac Clearance vs G60 Hip Frailty Index

The primary objective of this study is to establish a data repository that will be permissive of quality improvement studies/observations specific to postoperative mortality outcomes for geriatric patients with orthopedic injuries based on Orthopedic Hip Frailty Score and preoperative cardiac clearance predictors.

60 years of age All Phase N/A

Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions

This study has the goal to increase physical activity and fitness among Latinos in San Diego, California and Mexicali, Baja California (U.S.-Mexico border) since these cities have similar diseases such as high rates of heart disease and obesity. Therefore there is a need to have physical activity programs for children …

6 years of age All Phase N/A

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