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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,881 clinical trials
H Hung-Jui Chuang, MD

The Effect of a Smartphone-assisted Hybrid Cardiac Rehabilitation Program in Patients With Heart Failure.

The aim of this randomized controlled trial is to compare the impact of a case manager-led smartphone-assisted hybrid cardiac rehabilitation program with usual care in patients with HF. Participants will undergo a 12-week program led by a case manager and assisted by a smartphone. The study aims to answer two …

18 - 80 years of age All Phase N/A
M Miao

SOCIAL_HF: Improving Social Frailty Through Interactive Learning

The goal of this clinical trial is to learn whether the WeChat-based program "Social Optimization Chat for Interactive Learning for Heart Failure" (SOCIAL\_HF) can improve social frailty in elderly patients with heart failure. The main questions it aims to answer are: Can a 6-week WeChat online group interactive learning program …

60 years of age All Phase N/A
B Baldeep Sidhu, MD

Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk

This study will evaluate the Heartfelt device, a novel, passive monitoring system that detects early signs of fluid build-up in patients (oedema) with heart failure by measuring changes in foot and lower leg volume through capture of 3D images. The trial will assess whether this device, when added to standard …

18 years of age All Phase N/A
J Julia González González

Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure (SANDI STUDY)

The goal of this observational study is to assess the natriuretic effect of intravenous acetazolamide in patients admitted with heart failure and persistent congestion despite treatment with intravenous furosemide and sodium-glucose cotransporter type 2 (iSGLT2) inhibitors. The main question it aims to answer is whether there is a difference in …

years of age All Phase N/A
Y Yuki Kuramochi, BSN, RN

Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia

ASCEND is a randomized controlled open-label pilot study evaluating the safety and effectiveness of pulsed field ablation (PFA) with the novel FARAPOINT catheter compared to the standard radiofrequency (RFA) ablation with FlexAbility SE or ThermoCool ST catheter for ablation of ventricular tachycardia (VT) in the patients with ischemic cardiomyopathy and …

18 years of age All Phase N/A
C Chun Ka Wong, Clinical Assistant Professor

Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status Trial

Repaired Tetralogy of Fallot (rTOF) is the leading cause of congenital cyanotic heart disease worldwide, involving up to 7-10% of congenital heart disease. With advances in open-heart surgical repair techniques and medical therapies, there is a significant increase in patients with rTOF surviving till late adulthood. One sequalae that nearly …

18 years of age All Phase 4
L Luka Percin, MD

Impact of Coronary Sinus Flow Reducer on Coronary Microcirculation and Myocardial Ischemia

The increasing number of coronary revascularization procedures, coupled with improvements in drug therapy, has significantly extended the lifespan of patients with coronary artery disease (CAD). However, there remains a significant number of CAD patients who experience disability due to chronic refractory angina pectoris. These patients typically have severe diffuse CAD …

18 - 90 years of age All Phase N/A
S Suk Ho Sohn, MD

Effect of Left Posterior Pericardiotomy for the Prevention of POAF

This study is planned to evaluate the effect of left posterior pericardiotomy for the prevention of postoperative atrial fibrillation after coronary artery bypass grafting. Eligible patients will be randomized to be created or not to be created the left posterior pericardiotomy at the end of the operation, and the incidence …

19 years of age All Phase N/A
D Demetra Christou, PhD

Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function

Older adults with coronary artery disease (CAD) have impaired vascular and inspiratory muscle function. The objective of this study is to examine the effect of beet juice supplementation on vascular and inspiratory muscle function in older adults with CAD.

60 - 85 years of age All Phase N/A
I Iñigo Lozano, MD, PHD

Cross-over Study of Coronary Risk Factors With a Polypill

Open-label, randomized, cross-over study conducted in a single center, applied to patients receiving a polypill with 100 mg of acetyl salicylic acid and different doses of ramipril and atorvastatin for indication of secondary prevention according to clinical practice, with objective of analyzing the level of systolic blood pressure and LDL-cholesterol …

18 years of age All Phase 4

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