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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,879 clinical trials
R REVALVE Study Manager

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

Transcatheter aortic valve implantation (TAVI) is a key-hole technique to replace an aortic heart valve that is narrowed and/or leaking. Although TAVI is a safe and effective treatment for a faulty aortic heart valve, the new TAVI valve will not last forever. Because it is a 'tissue' valve (made from …

18 years of age All Phase N/A
H Holger Nef, Prof., MD

The Prospective Segeberg Registry for Mitral Transcatheter Edge-to-Edge Repair

A Prospective Follow-up Assessment in Bad Segeberg for Patients with severe MR undergoing M-TEER

18 - 100 years of age All Phase N/A
R Rachel Lemont

Clinical Course Of Disease In Participants With FA-CM

Characteristics and clinical course of disease In participants with cardiomyopathy associated with Friedreich Ataxia (CLARITY-FA)

6 years of age All Phase N/A
T Toru Naganuma, M.D.

Isolated Surgical Aortic Valve Replacement in Low Risk AS Patients

To establish the safety and effectiveness of surgical aortic valve replacement (SAVR) in patients with isolated severe, calcific aortic stenosis who are at low surgical risk.

years of age All Phase N/A
J Jodi Darring

AltaValve Pivotal Trial

This is a prospective, single arm, multicenter, clinical trial designed to evaluate the safety and performance of the AltaValve System for the treatment of mitral regurgitation in a targeted patient population.

18 years of age All Phase N/A
X Xiaodong Zhuang, Dr

MItral Regurgitation Risk Assessment and CLinical modElling

Mitral regurgitation (MR) is a common valvular heart disease worldwide, and untreated severe MR is associated with an elevated risk of heart failure and mortality. According to causes, MR could be divided into primary or secondary MR. The risk factors of mortality or heart failure hospitalization in different types of …

18 years of age All Phase N/A

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve systems in subjects with moderate, calcific aortic stenosis. Following completion of enrollment, subjects will be eligible for enrollment in the continued access phase …

65 years of age All Phase N/A
L Lin Zhang, M.D.

PRogression of Atheroma Evaluated by CT Angiography and IntraCoronary Imaging tEchniques

This is a combined cohort study with retrospectively and prospectively enrolled coronary artery disease (CAD) patients. All the patients will undergo clinical follow-up for up to 5 years, and repeat coronary CTA will be conducted after 2 years. Comprehensive morphological and functional plaque analysis will be performed. The impact of …

18 years of age All Phase N/A
V Vincent Letocart, MD

HighFLO Study - HighLife Trans-septal Mitral Valve Replacement (TSMVR) Feasibility Study of the Open Cell CLARITY Valve

Feasibility, safety and performance of the HighLife CLARITY TSMV and its delivery system

18 years of age All Phase N/A
K Ketevan Gabunia, MD

Feasibility Study of the Tioga TMVR System

The study is aimed to assess the safety and feasibility of the Tioga TMVR System in treating patients with symptomatic MR (MR\>=3+)

18 years of age All Phase N/A

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