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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,650 clinical trials
D Director of Clinical Trial Administration Office, Mr. Aoki

A Clinical Evaluation of AMJ-401

A Clinical Evaluation of AMJ-401 in the Treatment of Subjects with Ischemic Heart Disease in Japan

18 years of age All Phase N/A
H Hélène Bouvaist, MD

OPTImal Treatment of Sinus VENOSUS Defect

Sinus venosus defect (SVD) accounts for 10% of atrial septal defects and is characterized by an anomalous pulmonary venous return in the superior vena cava associated with a high situated atrial septal defect. Since 2013, transcatheter correction of this congenital heart disease has emerged as a new treatment option. The …

12 years of age All Phase N/A
M Michelle Gurvitz, MD

The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults

The main purpose of this proposal is to perform novel MRI analyses to determine the brain organizational changes associated with altered executive function and the modulating role of variants in neuroresilience and hypoxia response genes in adults with d-transposition of the great arteries (d-TGA).

24 - 35 years of age All Phase N/A
L Lauren Allen

Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery

To evaluate if there is any clinical difference in patients 3.5-12kg who undergo cardiac surgery with cardiopulmonary bypass that do and do not receive blood products as part of their procedure. The main hypothesis of the study is that the patients undergoing bloodless cardiac surgery will have decreased morbidity and …

years of age All Phase N/A
S Seyeon Park

Effect of Local Warming for Arterial Catheterization in Pediatric Anesthesia

The increase in internal diameter (ID) and cross-sectional area (CSA) may facilitate better arterial catheterization. Since an increase in body temperature can cause peripheral vasodilation, we aimed to determine if local warming of the radial artery (RA) catheterization site could improve the success rate of catheterization in pediatric patients.

- 2 years of age All Phase N/A

Online Support 4 CHD Kids & Caregivers

This study will evaluate a virtual mental health parenting stepped-care intervention (I-InTERACT-North) to determine if the program works to improve positive parenting skills and child behaviour among families with children born with Congenital Heart Disease (CHD). Recruitment will target children ages 3-9 years old from SickKids. We will also evaluate …

3 - 9 years of age All Phase N/A
E Emma Salmon, BS

Parent Navigator Program (PNP) to Improve Outcomes in Latino/x Children and Parents

The goal of this clinical trial is to see if a Parent Navigator Program (PNP) is helpful for Latino/x parents of babies with congenital heart disease (CHD) to get connected to developmental follow-up services. The main question it aims to answer are: Do families assigned to the Parent Navigator Program …

years of age All Phase N/A

HFNC vs NIPPV Following Extubation

This study has the goal to determine the best method of respiratory support following extubation after cardiac surgery (CS). After cardiac surgery for Congenital Heart Disease (CHD), patients remain intubated until the cardiac team determines it is safe for the patient to undergo a trial of extubation. Two common methods …

- 1 years of age All Phase N/A
S Silvia Salvi

Preeclampsia and Fetal Heart Malformations: Looking to Maternal Heart

The goal of this study is to describe the maternal hemodynamic parameters detected by UltraSonic Cardiac Output Monitor (USCOM®) in women carrying a fetus with a congenital heart disease (CHD) and to possibly describe an association between those parameters and the presence of a fetal cardiac anomaly. It will also …

18 years of age Female Phase N/A
Y Yuehong Ren

Application of Ultrasound Technique in Locating the End of the Gastric Tube in Children Aged 0-6 Years

Application of ultrasound technique to locate the end of the gastric tube in children aged 0-6 years

1 - 6 years of age All Phase N/A

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