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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,826 clinical trials
L Linda Pastorius

The WiSE®-UP Registry (The WiSE System Utilization & Performance Registry)

Observe to understand product performance, including patient safety, clinical outcomes, and CRT response information associated with the use of the market-released WiSE System

years of age All Phase N/A
S Stefano Ghio, PI

Registry of Pavia Chronic Heart Failure Patients-observational Study

Registry of Pavia chronic heart failure patients-observational study

18 years of age All Phase N/A
N Nils Daum

Intensive Care Unit-acquired Heart Failure in Critically Ill: the ICU-HF Study

Critically ill patients in intensive care units (ICUs) are exposed to a wide range of complications that can affect long-term morbidity and mortality. Not only the initial diagnosis at the time of admission may lead to complications; the ICU stay itself can also be associated with specific disease patterns. One …

18 years of age All Phase N/A
H Harm Wienbergen

Intensive Prevention Program After Decompensated Heart Failure

Introduction: Care for patients with heart failure (HF) often remains inadequate, even though a variety of treatment options exist. Guideline-based, multimodal therapy is rarely fully established, partly due to insufficient intersectoral cooperation and insufficient patient training. Heart failure nurses (HFN) as specialized non-medical personnel are intended to contribute to better …

18 - 80 years of age All Phase N/A
S Svetlana Rachina

Patient-Reported Health Status Assessment Using the KCCQ for Early Detection of Heart Failure Worsening

This observational feasibility study aims to assess (i) how practical and acceptable repeated KCCQ assessments are; (ii) the connection between changes over time in KCCQ scores and signs of congestion; and (iii) clinical outcomes, including worsening heart failure events or cardiovascular death (CVD), and the time between 5- and 10-point …

18 years of age All Phase N/A
S Samson S. Badalyan, MD, PhD

Effect of Dapagliflozin on Right Ventricular-Pulmonary Artery Coupling After Off-Pump Coronary Atery Bypass Grafting

This prospective, single-center observational study evaluates the effect of dapagliflozin 10 mg/day on right ventricular-pulmonary artery coupling measured by the TAPSE/PASP ratio in 72 patients with left ventricular ejection fraction \<50% after off-pump coronary artery bypass grafting (OPCAB). The primary outcome is the change in TAPSE/PASP ratio from 1 month …

18 years of age All Phase N/A
B Bonnie Ostergren

CALM Study: Cardiomems Assisted Lvad Management

This prospective, open label, randomized, single-center pilot clinical trial will determine if the rate of heart failure related (HFR) hospitalizations is less in LVAD patients whose PAP is monitored with the CardioMEMS device vs the control patients receiving standard of care treatment.

21 - 85 years of age All Phase N/A
R Rengin Demir, Prof. Dr.

Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure

The goal of this clinical trial is to evaluate whether dual-task inspiratory muscle training (IMT) is effective in improving cognitive and functional outcomes in adults with heart failure. It will also assess the effects of standard IMT and compare both approaches. The main questions it aims to answer are: Does …

40 years of age All Phase N/A
A Amber Woltzen

Community-Informed Interventions for Equitable Congestive Heart Failure Management in Primary Care

The purpose of this study is to expand subject matter expertise and sustained capacity for equity-oriented care within the Advanced Care Ecosystem (ACE) by engaging patients, caregivers, community health workers (CHW), and care-team stakeholders in development work focused on adults living with congestive heart failure (CHF) and adverse social determinants …

18 years of age All Phase N/A
O Olivier Hanon, MD PhD

Relevance of Artificial Intelligence-Assisted Echocardiography for Left Ventricular Ejection Fraction Assessment in Geriatric Patients

Heart failure (HF) is the leading cause of hospitalization among adults aged 80 years and older and represents a major diagnostic challenge in geriatric medicine due to frequently atypical clinical presentations and the presence of multiple comorbidities. Although transthoracic echocardiography (TTE) with measurement of left ventricular ejection fraction (LVEF) remains …

75 years of age All Phase N/A

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