Advanced Filters
noise

Liver Disease Clinical Trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,453 clinical trials

Multidimensional Frailty Assessment and Post-Transplant Outcomes in Liver Transplant Candidates

This study will evaluate frailty, nutrition, sarcopenia, and psychological health in people waiting for a liver transplant. The purpose is to understand how these factors affect outcomes before and after transplantation. By identifying patients at higher risk early, the study aims to support the development of better care programs in …

18 - 65 years of age All Phase N/A
Q Q.J.J. Augustijn, MD

Synbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis

The goal of this clinical trial is to investigate the therapeutic potential of A. soehngenii and pasteurized A. muciniphila combined with B. animalis subsp. lactis and fructo-oligosaccharides with and without conditioned vegan lyophilized fecal microbiota transplantation capsules to reduce NASH in patients with fibrotic NASH. The main questions to answer …

18 - 75 years of age All Phase 2
A Adam T Whaley-Connell, DO MSPH

Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans

Nonalcoholic steatohepatitis (NASH) is the aggressive form of nonalcoholic fatty liver disease, which is rapidly becoming a worldwide public health problem. It is more common in the military and Veteran population compared to the general US population. NASH may progress to end-stage liver disease and primary liver cancer, and hence …

18 - 75 years of age All Phase 2
J Joshua R. Cook, MD, PhD

Human Models of Selective Insulin Resistance: Alpelisib, Part I

The goal of this clinical trial is to understand how the blood sugar-lowering hormone insulin works in healthy adults versus those who are at risk for type 2 diabetes. The study will use a drug called alpelisib, which interferes with insulin's actions in the body, to answer the study's main …

18 - 70 years of age All Phase 1
C Clinical Study Center

Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI

The aim of the prospective observational DISTEMI-Study in people with and without Diabetes mellitus (DI) after new onset of ST-Segment Elevation Myocardial Infarction (STEMI) aged 18-80 years at inclusion into the study is to characterize in detail the clinical, metabolical, immunological and vascular phenotype, investigate the interplay between myocardial remodelling …

18 - 80 years of age All Phase N/A
X Xiaopeng Cai

Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis

This clinical trial aims to determine whether phycocyanin, a natural protein derived from spirulina, can help treat liver fibrosis or cirrhosis in adult patients. The main questions it aims to answer are: Can phycocyanin reduce blood levels of liver enzymes (such as ALT and AST) that indicate liver damage? Can …

18 - 75 years of age All Phase N/A
a ana cruceta

Efficacy of Simvastatin in Alcoholic Liver Fibrosis

Evaluate the efficacy of simvastatin in reducing liver fibrosis in patients with advanced fibrosis due to alcohol

18 years of age All Phase 2/3

Adverse Outcomes and Mortality in Liver Transplant

Prospective natural history pilot study to explore the link between muscle composition using an MRI-based Muscle Assessment Score (MAsS) and adverse outcomes in liver transplant candidates.

18 years of age All Phase N/A
T Thomas Reiberger, MD

Austrian Registry on Transjugular Intrahepatic Portosystemic Shunts

Patients with TIPS will be recruited in this prospective registry study. The clinical course will be documented and biomarkers for prediction of complicatiosn will be assessed.

18 - 99 years of age All Phase N/A

Clinical Study of PTFE Covered Stent for Treating Portal Hypertension

To validate the safety and efficacy of TIPS (Transjugular Intrahepatic Portosystemic Shunt) using PTFE covered stent in the treatment of portal hypertension.

18 - 85 years of age All Phase N/A

Simplify language using AI