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Liver Disease Clinical Trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,453 clinical trials
L Luca Vittorio Carlo Valenti

Human Liver ORganoids as a Model to Study the Development of Non-Alcoholic SteatOhepatitis (NASH)

The primary objective of the study is to generate and characterize three-dimensional models, called "assembloids", composed of the main liver cell populations (in particular from the co-culture of organoids with stellate cells, responsible for fibrogenesis, deriving from clinical samples). These models will be used in order to imitate the first …

18 years of age All Phase N/A

Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes

This Phase 2a clinical trial is a dose escalation study of the safety, tolerability, and efficacy of hepatocyte transplantation into lymph nodes via endoscopic ultrasound among subjects with end-stage liver disease.

18 - 70 years of age All Phase 2
A Adam J Milam, MD

Disparities Among Liver Transplant Patients

The purpose of this study is to inform healthcare interventions to reduce the disparities in liver transplant listing and in transplantation.

18 - 65 years of age All Phase N/A
S Sofia Penazza

Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With Fibrosis

The purpose of the KETONASH study is to evaluate, in patients with metabolic-associated fatty liver disease (MAFLD) with non-alcoholic steatohepatitis (NASH) and significant liver fibrosis, the effect of a very low-calorie ketogenic diet (VLCKD) compared to that of a standard low-calorie diet (standard Mediterranean LCD - in accordance with the …

18 years of age All Phase N/A
J Jur Kroon, BSc

Effect of Timed-Restricted Eating on Metabolic Health

We aim to determine the effect of combined isocaloric time restricted eating and meal timing on metabolic health, liver fat, functional brain networks, inflammation, and sleep pattern/quality in subjects with obesity and insulin resistance.

50 - 75 years of age All Phase N/A
L Laura A Huidobro, MD, PhD

Prevention of NAFLD and CVD Through Lifestyle Intervention

Prevention of non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD) through lifestyle intervention (MAUCO+) is a clinical trial that aims to improve sarcopenia, aerobic capacity, body composition, and lipid profile, insulin resistance, cardiovascular risk, NAFLD, and maintain a healthier lifestyle. Through the implementation of physical activity and nutritional programs.

45 - 60 years of age All Phase N/A
S Salvatore Accomando, MD

Liver Steatosis in Pediatric CD Patients

Celiac disease (CD) is an autoimmune enteropathy triggered by the intake of gluten, characterized by a genetic predisposition. Although, CD is often associated with malabsorption symptoms, a growing number of affected subjects are overweight or frankly obese. One of the conditions that is most frequently detected in pauci/asymptomatic subjects is …

1 - 14 years of age All Phase N/A
A Ali Ismail, lecturer

Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Aerobic Exercise

Familial Mediterranean fever (FMF) affect liver and causes some dysfunctions including non-alcoholic fatty liver.. still exercise and diet limitation is the treatment for this case

30 - 55 years of age Female Phase N/A
B Benjamin Maasoumy, MD

Health Literacy and Self-efficacy Expectations in Patients With Alcohol-related Liver Cirrhosis

The goal of this observational study is to quantify the health literacy and self-efficacy in people with alcohol-related liver cirrhosis.

18 - 99 years of age All Phase N/A
N Nikhil Pai, MD

Soluble Fibre Supplementation in NAFLD

The FIND study will look at the effect of a nutritional mixed fibre supplement, oligofructose and inulin (OF+INU), on children with non-alcoholic fatty liver disease. In this randomized, double- blind controlled trial, subjects will be given a supplement, in the form of oral pills, and will have bloodwork performed, their …

8 - 17 years of age All Phase 2

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