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Liver Disease Clinical Trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,492 clinical trials
A Annette Bellar, BS

Comparison of ALD, NASH, and Healthy Control Patients

The availability of biological samples from individuals with alcoholic liver disease (ALD), as well as samples from appropriate heavy drinking, yet healthy controls and non-drinking healthy controls, is an essential first step in the translation of basic research advances to the clinic. The purpose of the Clinical Core component of …

21 - 75 years of age All Phase N/A
R Revathi Penumatsa

Ethanol Induces Skeletal Muscle Autophagy

In this study we plan to demonstrate that ethanol induces skeletal muscle autophagy to degrade MAA adducts.

18 - 65 years of age All Phase N/A
y yewei zhang

Recurrent Liver Cancer: Reconceptualization and Reevaluation

The goal of this observational study is to determine if a specific protein can serve as a novel indicator for the recurrence of liver cancer. The study will focus on recurrent liver cancer patients and compare participants to primary liver cancer patients as controls. The primary purpose is to assess …

18 - 75 years of age All Phase N/A

MR Guidance for Liver and Pancreas

This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may provide information that could potentially be used during the treatment to improve the …

18 years of age All Phase N/A
B Benjamin Maasoumy, MD

TIPS in Patients With Decompensated Liver Cirrhosis

This is a single center patient registry of patients receiving a transjugular intrahepatic portosystemic shunt (TIPS) at Hannover Medical School. By collecting and analyzing clinical data as well as blood samples, the overall aim is to optimize TIPS therapy (e.g. specify selection criteria).

18 - 99 years of age All Phase N/A
D Daren Liu, MD, PhD

Exploration of Gender Differences in Liver Aging

The liver is an important metabolic organ in the body. It participates in central metabolic activities to maintain systemic homeostasis. It is also one of the most vulnerable organs in the process of individual aging. During aging, the volume, blood flow, metabolic capacity and regenerative capacity of the liver decrease. …

18 - 80 years of age All Phase N/A
Q Qin Zhang, phd

Liver Ischemia-reperfusion Injury and Clinical Data Analysis

Searching for new targets for the diagnosis and treatment of liver ischemia-reperfusion injury.

18 - 70 years of age All Phase N/A
Y Yu Shi, MD

MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases

The goal of this study is to investigate the value of MR elastography-based SII as a means of detecting HGP noninvasively in patients with pathology-proven CRLM. MRE will provide a direct measure of tumor-liver adhesion to investigate the relationship between imaging findings and pathophysiological changes in the Liver.

18 - 80 years of age All Phase N/A
G Giulia Piaggio, Biologist

Development of Organoids From Primary Colorectal Tumors and Synchronous Liver Metastases

Pilot feasibility study for the development of organoids from primary colorectal tumors and synchronous liver metastases, to prepare organoids from primary colorectal tumors and synchronous liver metastases. The organoids will allow us to study the function of genes targeted by the activity of the NF-Y/p53 complex.

18 years of age All Phase N/A
P Philippe Klee, MD-PhD

Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function

The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism. The values will be compared to those obtained in healthy volunteers. The aim of the study is to test the …

12 - 16 years of age All Phase N/A

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